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3.1.27.8: Ribonuclease V

This is an abbreviated version!
For detailed information about Ribonuclease V, go to the full flat file.

Word Map on EC 3.1.27.8

Reaction

hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP =

Synonyms

endonuclease V, EndoV, FLJ35220, FLJ35220 protein, hEndoV

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.27 Endoribonucleases producing 3'-phosphomonoesters
                3.1.27.8 Ribonuclease V

Engineering

Engineering on EC 3.1.27.8 - Ribonuclease V

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
C225S
site-directed mutagenesis, the mutant shows significantly reduced enzyme activity compared to the wild-type full-length enzyme
C226S
site-directed mutagenesis, the mutant shows significantly reduced enzyme activity compared to the wild-type full-length enzyme
C227S
site-directed mutagenesis, the mutant shows significantly reduced enzyme activity compared to the wild-type full-length enzyme
C228S
site-directed mutagenesis, the mutant shows significantly reduced enzyme activity compared to the wild-type full-length enzyme
D52A
site-directed mutagenesis of an active site residue, inactive mutant
E100A
site-directed mutagenesis of an active site residue, the mutant shows highly reduced activity compared to the wild-type enzyme
Y91A
site-directed mutagenesis of an active site residue, the mutant shows highly reduced activity compared to the wild-type enzyme
additional information