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3.1.26.9: ribonuclease [poly-(U)-specific]

This is an abbreviated version!
For detailed information about ribonuclease [poly-(U)-specific], go to the full flat file.

Reaction

endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups =

Synonyms

nuclease, ribo- (uracil-specific), ribonuclease, ribonuclease (uracil-specific), uracil-specific endoribonuclease, uracil-specific RNase

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.26 Endoribonucleases producing 5'-phosphomonoesters
                3.1.26.9 ribonuclease [poly-(U)-specific]

Inhibitors

Inhibitors on EC 3.1.26.9 - ribonuclease [poly-(U)-specific]

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Cu2+
-
-
Fe2+
-
-
Hg2+
-
-
human placental RNase inhibitor protein
-
halves the RNase activity
-
NEM
-
slight
additional information
-
DTT and beta-mercaptoethanol do not inhibit the activity; no inhibition by dithiothreitol and beta-mercaptoethanol
-