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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules structure-function study, substrate recognition and catalytic mechanism of the ribozyme
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules structure-function study, substrate recognition and catalytic mechanism of the ribozyme
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, amino acids residues Arg90, Arg107, Lys123, Arg176, and Lys196 are involved in interaction with enzyme RNA or with the pre-tRNA
endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, chloroplast enzyme does not use the ribozyme-type pre-tRNA cleavage mechanism, distinct from bacterial reaction mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, cleavage of ssRNA, mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, cleavage of ssRNA, mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, conserved residues in J5/15 are responsible for substrate affinity and specificity of the ribozyme, nucleotide base N(-1) is involved in substrate recognition in bacteria and archea
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, non-RNA-based cleavage mechanism, structure-function relationship of eukaryotic enzymes
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, reaction mechanism in 3 consecutive steps: pre-tRNA binding, hydrolysis of the scissile phosphodiester bond, generating a 3'-hydroxyl and a 5'-phosphate group, possibly via a trigonal bipyramide, intermediate, and the dissociation of the mature tRNA and the 5'-leader product, structure-function relationship of eukaryotic enzymes
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, reaction mechanism in 3 consecutive steps: pre-tRNA binding, hydrolysis of the scissile phosphodiester bond, generating a 3'-hydroxyl and a 5'-phosphate group, possibly via a trigonal bipyramide, intermediate, and the dissociation of the mature tRNA and the 5'-leader product, substrate recognition mechanism, overview, structure-function realtionship of eukaryotic enzymes
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, RNA-based catalytic mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, secondary structural features, e.g. helix P4, sequence J5/15 or J18/2 in the RNA portion of the enzyme, are important for catalysis
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, structure-function study, substrate recognition and catalytic mechanism of the ribozyme
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, substrate recognition mechanism, detection methods, the RNA and protein subunits cooperate to bind different portions of the substrate structure, with the RNA subunit predominantly interacting with the mature domain of tRNA and the protein interacting with the 5'-leader sequence, substrate recognition and binding, reaction mechanism and detection methods
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, substrate recognition, enzyme possesses a single-stranded RNA binding cleft that interacts with the unpaired 5'-leader
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, the protein subunit is essential for substrate binding, the RNA subunit is essential for catalysis
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, the protein subunit is essential for substrate binding, the RNA subunit is essential for catalysis
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, the RNA subunit is essential for catalytic activity, divalent metal ion-dependent in-line SN2 displacement mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, the RNA subunit is essential for catalytic activity, divalent metal ion-dependent in-line SN2 displacement mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, the RNA subunit is essential for catalytic activity, divalent metal ion-dependent in-line SN2 displacement mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, the RNA subunit is essential for catalytic activity, divalent metal ion-dependent in-line SN2 displacement mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, the RNA subunit is essential for catalytic activity, divalent metal ion-dependent in-line SN2 displacement mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, the RNA subunit is essential for catalytic activity, divalent metal ion-dependent in-line SN2 displacement mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, the RNA subunit is essential for catalytic activity, except for the mitochondrial enzyme, divalent metal ion-dependent in-line SN2 displacement mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, the RNA subunit is the catalytic unit, while protein subunit Rpp25 is involved in RNA substrate binding, both interact with each other
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism, CR-IV region is imporatnt for tRNA binding
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism, CR-IV region is important for tRNA binding
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, tRNA precursor substrate recognition and cleavage mechanism, structure-function relationship of the RNA subunit
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endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor
an RNA-containing enzyme, essential for tRNA processing, generates 5'-termini or mature tRNA molecules, amino acids residues Arg90, Arg107, Lys123, Arg176, and Lys196 are involved in interaction with enzyme RNA or with the pre-tRNA
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