3.1.26.11: tRNase Z

This is an abbreviated version!
For detailed information about tRNase Z, go to the full flat file.

Reaction

endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule =

Synonyms

(tRNase) Z, 3 tRNase, 3' tRNase, 3'-tRNA processing endoribonuclease, 3'-tRNase, AthTrz1, AthTrz2, AthTrz3, AthTrz4, BsuTrz, CelTrz, DmeTrz, EcoTrz, EcoZ, Elac, Elac1, ELAC2, HsaTrz1, HsaTrz2, HvoTrz, long form of 3' tRNase, long form of tRNA 3' processing endoribonuclease, long form of tRNase Z, MjaTrz, nuclease, transfer ribonucleate maturation 3'-endoribo-(9CI), PaeTrz, pre-tRNA processing endoribonuclease, precursor tRNA 3'-end processing endoribonuclease, ribonuclease Z, RNase BN, RNase Z, RNase ZL, RNase ZS1, RNaseZ, RNZ, SceTrz, SpTrz1p, SpTrz2p, TM0207, TmaTrz, TMS5 protein, transfer RNA maturation endonuclease, tRNA 3 endonuclease, tRNA 3' processing endoribonuclease, tRNA 3'-processing enzyme tRNase Z, tRNA precursor-processing endoribonuclease, tRNase Z, tRNase Z2, tRNase ZL, tRNase ZS, tRNaseZ, tRnaseZL, tRnaseZS, Trz, TRZ1, Trz1p, TRZ2, TrZL1, TrZL2, TrZS1, TrZS2, YP_145327, YqiK, YqjK, zinc phosphodiesterase, zinc-dependent phosphodiesterase, ZiPD

ECTree

     3 Hydrolases

         3.1 Acting on ester bonds

             3.1.26 Endoribonucleases producing 5'-phosphomonoesters

                3.1.26.11 tRNase Z

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Results	in table
4	Activating Compound
21007	AA Sequence
1	Application
1	CAS Registry Number
61	Cloned(Commentary)
15	Crystallization (Commentary)
207	Disease/ Diagnostics
4	Expression
45	General Information
27	Inhibitors
4	kcat/KM [mM/s]
67	KM Value [mM]
91	Localization
54	Metals/Ions
23	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
238	Organism
13	PDB ID
18	pH Optimum
4	pI Value
207	Protein Variants
42	Purification (Commentary)
1	Reaction
36	Reaction Type
225	Reference
49	Source Tissue
12	Specific Activity [micromol/min/mg]
305	Substrates and Products (Substrate)
26	Subunits
443	Synonyms
22	Temperature Optimum [°C]
1	Temperature Stability [°C]
23	Turnover Number [1/s]

Expression

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Expression on EC 3.1.26.11 - tRNase Z

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

all tRNase Z genes are expressed during all growth stages of Arabidopsis, in particular during the first stage of development (seedling) and at the start of flowering

Arabidopsis thaliana

Q8L633, Q8LGU7

710310

siRNA targeting the tRNase ZL mRNA

Homo sapiens

-

710364

trz2 is expressed at a very low level. The TATA-like element is essential for trz2 expression. The low-level trz2 expression may arise from a low level of transcription caused by lack of a strong TATA box and the negative regulatory element (NRE)

2 entries

trz2 is expressed at a very low level. The TATA-like element is essential for trz2 expression. The low-level trz2 expression may arise from a low level of transcription caused by lack of a strong TATA box and the negative regulatory element (NRE)

Schizosaccharomyces pombe

P87168, Q10155

751507

trz2 is expressed at a very low level. The TATA-like element is essential for trz2 expression. The low-level trz2 expression may arise from a low level of transcription caused by lack of a strong TATA box and the negative regulatory element (NRE)

Schizosaccharomyces pombe ATCC 24843

-

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