3.1.26.1: Physarum polycephalum ribonuclease
This is an abbreviated version!
For detailed information about Physarum polycephalum ribonuclease, go to the full flat file.
Reaction
Endonucleolytic cleavage to a 5'-phosphomonoester =
Synonyms
RNase Phyb
ECTree
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Substrates Products
Substrates Products on EC 3.1.26.1 - Physarum polycephalum ribonuclease
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REACTION DIAGRAM
RNA + H2O
5'-phosphonucleotide
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low molecular weigt yeast RNA
product identification
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RNA + H2O
mononucleotides
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yeast RNA, base specificity of B1 site is A,G,U > C and of B2 A > G > C > U, depolymerization
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additional information
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substrate specificity of RNase Phy I and II, the latter shows a preference for GpN substrates, while rejecting ApN dinucleotide substrates, RNase I shows a preference for ApN before GpN substrate, while CpN dinucleotides are rather resistant against hydrolysis, overview
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