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3.1.21.8: T4 deoxyribonuclease II

This is an abbreviated version!
For detailed information about T4 deoxyribonuclease II, go to the full flat file.

Word Map on EC 3.1.21.8

Reaction

endonucleolytic nicking and cleavage of cytosine-containing double-stranded DNA =

Synonyms

denA, EndoII, endonuclease II, endonuclease IV, GIY-YIG enzyme, T4 endonuclease II

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.21 Endodeoxyribonucleases producing 5'-phosphomonoesters
                3.1.21.8 T4 deoxyribonuclease II

Natural Substrates Products

Natural Substrates Products on EC 3.1.21.8 - T4 deoxyribonuclease II

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
DNA + H2O
?
show the reaction diagram
Tequatrovirus T4
the phage T4 enzyme is involved in degradation of host DNA
-
-
?
DNA where cytosine is partially or completely replaced by hydroxymethylcytosine + H2O
?
show the reaction diagram
Tequatrovirus T4
DNA where cytosine is partially or completely replaced by hydroxymethylcytosine is degraded in vivo by T4 endonuclease II, EC 3.1.21.8, and endonuclease IV, EC 3.1.21.9
-
-
?