3.1.21.8: T4 deoxyribonuclease II

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For detailed information about T4 deoxyribonuclease II, go to the full flat file.

Reaction

endonucleolytic nicking and cleavage of cytosine-containing double-stranded DNA =

Synonyms

denA, EndoII, endonuclease II, endonuclease IV, GIY-YIG enzyme, T4 endonuclease II

ECTree

     3 Hydrolases

         3.1 Acting on ester bonds

             3.1.21 Endodeoxyribonucleases producing 5'-phosphomonoesters

                3.1.21.8 T4 deoxyribonuclease II

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Results	in table
8	AA Sequence
3	Cloned(Commentary)
2	Crystallization (Commentary)
1	General Information
3	Inhibitors
5	Metals/Ions
2	Natural Substrates/ Products (Substrates)
8	Organism
1	pH Optimum
17	Protein Variants
1	Reaction
8	Reference
6	Substrates and Products (Substrate)
9	Synonyms
1	Temperature Optimum [°C]
1	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 3.1.21.8 - T4 deoxyribonuclease II

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

Mg2+

Tequatrovirus T4

P07059

above 10 mM

725989

NaCl

Tequatrovirus T4

P07059

above 50 mM

725989

additional information

Tequatrovirus T4

P07059

endonuclease IV activity is almost completely inhibited in the presence of very small amounts of hydroxymethylcytosine in the DNA

727596

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