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3.1.21.2: deoxyribonuclease IV

This is an abbreviated version!
For detailed information about deoxyribonuclease IV, go to the full flat file.

Word Map on EC 3.1.21.2

Reaction

Endonucleolytic cleavage of ssDNA at apurinic/apyrimidinic sites to 5'-phosphooligonucleotide end-products =

Synonyms

apurinic/apyrimidinic endonuclease, coliphage T4 endonuclease II, deoxriboendonuclease, DNA-adenine-transferase, E. coli endonuclease IV, EC 3.1.4.30, End, Endo IV, endodeoxyribonuclease IV, EndoII, EndoIV, endonuclease II, endonuclease IV, exonuclease III, More, MtbEndo IV, MtbNfo, MtbXthA, Nfo, nuclease, endodeoxyribo-oder redoxyendonuclease, Rv0670, Sco4631, ScoA3McrA, T4 endonuclease IV, TthNfo, type IV methyl-dependent restriction endonuclease

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.21 Endodeoxyribonucleases producing 5'-phosphomonoesters
                3.1.21.2 deoxyribonuclease IV

Activating Compound

Activating Compound on EC 3.1.21.2 - deoxyribonuclease IV

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
-
slight activation
bovine serum albumin
-
130% activity at 1% at pH 8.0 and 37°C
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additional information
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the enzyme is induced by phage T4, no activation by S-adenosyl-L-methionine, ATP, or both
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