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3.1.13.3: oligonucleotidase

This is an abbreviated version!
For detailed information about oligonucleotidase, go to the full flat file.

Word Map on EC 3.1.13.3

Reaction

exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates =

Synonyms

CpsORN, EC 3.1.4.19, More, nanoRNase, NrnC, nucleotidase, oligo-, oligoribonuclease, ORN, phosphodiesterase, REXO2, RNase T, small fragment nuclease, XC847, YtqI

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.13 Exoribonucleases producing 5′-phosphomonoesters
                3.1.13.3 oligonucleotidase

pH Range

pH Range on EC 3.1.13.3 - oligonucleotidase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7 - 9.5
-
pH 7.0: 50% of maximum activity, pH 9.5: 70% of maximum activity
8 - 10
-
nitrophenyl uridine 5'-monphosphate, pH 8: about 15% of maximum activity, pH 10: about 10% of maximum activity
additional information
-
active site highly acidic and substrate binding site highly basic