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3.1.13.2: exoribonuclease H

This is an abbreviated version!
For detailed information about exoribonuclease H, go to the full flat file.

Word Map on EC 3.1.13.2

Reaction

3'-end directed exonucleolytic cleavage of viral RNA-DNA hybrid =

Synonyms

3'-to-5' RNase H, HIV RNase H, HIV-1 ribonuclease H, HIV-1 RT ribonuclease H, LC11-RNase H1, More, Prp8, retroviral reverse transcriptase RNaseH, retroviral RNase H, reverse transcriptase ribonuclease H, reverse transcriptase-associated ribonuclease H, ribonuclease H, RNase H, RNase H1, RNase HI, RNaseH, RNH, RNH1, RT RNase H, RT/RNase H, T4 RNase H, Ta11

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.13 Exoribonucleases producing 5′-phosphomonoesters
                3.1.13.2 exoribonuclease H

Turnover Number

Turnover Number on EC 3.1.13.2 - exoribonuclease H

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0135
DNA-15-nucleotide-RNA hybrid
-
pH 7.8, 37°C, recombinant wild-type enzyme
-
0.017
DNA-16-nucleotide-RNA hybrid
-
pH 7.8, 37°C, recombinant wild-type enzyme
-
0.0018
DNA-17-nucleotide-RNA hybrid
-
pH 7.8, 37°C, recombinant wild-type enzyme
-
0.0032
DNA-18-nucleotide-RNA hybrid
-
pH 7.8, 37°C, recombinant wild-type enzyme
-
0.025 - 3.5
DNA-RNA hybrid
-
0.0024 - 0.0034
poly(rA)n-poly(dT)n
-
0.0024
poly(rA)n-poly(dT)ne
-
mutant p66C280P/p51
-
additional information
additional information
-