3.1.11.5: exodeoxyribonuclease V
This is an abbreviated version!
For detailed information about exodeoxyribonuclease V, go to the full flat file.
Word Map on EC 3.1.11.5
Reaction
Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides
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Synonyms
AddAB enzyme, E. coli ATP-dependent DNase, E. coli exonuclease V, Escherichia coli exonuclease V, Escherichia coli RecBCD, Exodeoxyribonuclease V 125 kDa polypeptide, Exodeoxyribonuclease V 135 KDA polypeptide, Exodeoxyribonuclease V 67 kDa polypeptide, exonuclease V, ExoV, gene recBC DNase, gene RecBC endoenzyme, nuclease, exodeoxyribo V, PAB2263, RecB, RecB helicase-nuclease, REcB30 protein, recBC deoxyribonuclease, recBC DNase, recBC nuclease, RecBCD, RecBCD DNase, recBCD enzyme, RecBCD exonuclease, RecBCD-type helicase-nuclease, RecD, UPF0286 protein PYRAB01260
ECTree
Application
Application on EC 3.1.11.5 - exodeoxyribonuclease V
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additional information
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AddA mutants that cannot bind or hydrolyze ATP are completely defective for DNA recombination
analysis
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no recombination in recB2109CD mutants
analysis
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possible role in genetic recombination
analysis
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cloning of palyndromic structures in the Physarum actin gene in E. coli lacking the recBC gene
analysis
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lack of enzyme increases transfection frequencies with linear DNA
analysis
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recBCD inhibits recombination between closely related bacteria
analysis
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recBCD inhibits recombination between closely related bacteria
analysis
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required for stability of plasmids