2.1.1.B84: cephaline 6'-O-methyltransferase

This is an abbreviated version!
For detailed information about cephaline 6'-O-methyltransferase, go to the full flat file.

Reaction

Synonyms

CiOMT1, IpeOMT1

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.B84 cephaline 6'-O-methyltransferase

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Results	in table
2	AA Sequence
2	Cloned(Commentary)
2	Cofactor
2	General Information
5	Inhibitors
4	kcat/KM [mM/s]
6	KM Value [mM]
2	Localization
1	Metals/Ions
1	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
3	Organism
3	pH Optimum
1	Purification (Commentary)
1	Reaction
3	Reference
3	Source Tissue
18	Substrates and Products (Substrate)
1	Subunits
3	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
4	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.1.1.B84 - cephaline 6'-O-methyltransferase

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S-adenosyl-L-methionine + 1alpha-(S)-N-deacetylisoipecoside

S-adenosyl-L-homocysteine + 6-O-methyl-N-deacetylisoipecoside

Carapichea ipecacuanha

the iminium cation, one of the spontaneous reaction products of 6-O-methyl-N-deacetylisoipecoside aglycon, might be an intermediate of emetine biosynthesis

720770

S-adenosyl-L-methionine + cephaeline

S-adenosyl-L-homocysteine + emetine

3 entries

additional information

Carapichea ipecacuanha

E7FL15

the enzyme is also active on 7'-O-demethylcephaeline forming cephaeline, overview

714532