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2.1.1.9: thiol S-methyltransferase

This is an abbreviated version!
For detailed information about thiol S-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.9

Reaction

S-adenosyl-L-methionine
+
a thiol
=
S-adenosyl-L-homocysteine
 +
a methyl thioether

Synonyms

AtHOL1, CrSMT1, HMT, HMT/HTMT, HTMT, Met S-methyltransferase, methionine S-methyltransferase, methyltransferase, thiol, MMT, OsHOL1, OsHOL2, PpSABATH1, S-adenosyl-L-methionine-dependent halide/thiol methyltransferase, S-adenosylmethionine-dependent halide/thiol methyltransferase, S-methyltransferase, S-methyltransferase 1, SABATH methyltransferase, SAM-dependent halide methyltransferase, thiol methyltransferase, thiol S-methyltransferase, TMT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.9 thiol S-methyltransferase

Inhibitors

Inhibitors on EC 2.1.1.9 - thiol S-methyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,3-dichloro-alpha-methylbenzylamine
2,3-dichloromethyl benzylamine
-
-
Ca2+
-
5 mM chloride salt, mild inhibitory effect, <25%, PpSABATH1
Cu2+
-
5 mM chloride salt, strong inhibitory effect, 50-100%, PpSABATH1
cystine
-
55% inhibition at 10 mM
Fe2+
-
5 mM chloride salt, strong inhibitory effect, 50-100%, PpSABATH1
Fe3+
-
5 mM chloride salt, strong inhibitory effect, 50-100%, PpSABATH1
iodoacetamide
-
55% inhibition at 10 mM
Mg2+
-
5 mM chloride salt, strong inhibitory effect, 50-100%, PpSABATH1
Mn2+
-
5 mM chloride salt, strong inhibitory effect, 50-100%, PpSABATH1
N-ethylmaleimide
p-chloromercuribenzoate
p-hydroxymercuribenzoic acid
-
95% inhibition at 10 mM, reversed in presence of 20 mM Cys
S-3-deazaadenosyl-L-homocysteine
-
-
S-adenosyl-L-homocysteine
-
-
S-Tubercidinyl-L-homocysteine
-
-
SKF 525A
additional information
-