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2.1.1.85: protein-histidine N-methyltransferase

This is an abbreviated version!
For detailed information about protein-histidine N-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
protein L-histidine
=
S-adenosyl-L-homocysteine
+
protein Ntau-methyl-L-histidine

Synonyms

actin His73 nmethyltransferase, actin histidine methyltransferase, actin histidine-N3 methyltransferase, actin-specific histidine methyltransferase, actin-specific histidine N-methyltransferase, actin-specific methyltransferase, methyltransferase, protein (histidine), protein (actin) histidine MTase, protein methylase IV, S-adenosyl methionine:protein-histidine N-methyltransferase, SET domain protein 3, setd3

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.85 protein-histidine N-methyltransferase

Inhibitors

Inhibitors on EC 2.1.1.85 - protein-histidine N-methyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
ATP
-
47% inhibition at 0.4 mM
Borate
-
slight inhibition
Ca2+
-
30% inhibition at 0.4 mM
EDTA
-
slight inhibition
K+
-
72% inhibition at 200 mM
Mg2+
-
60% inhibition at 8 mM
N-ethylmaleimide
-
70% inhibition at 4 mM
Na+
-
95% inhibition at 200 mM