2.1.1.79: cyclopropane-fatty-acyl-phospholipid synthase
This is an abbreviated version!
For detailed information about cyclopropane-fatty-acyl-phospholipid synthase, go to the full flat file.
Reaction
Synonyms
C17:cyclopropane synthase, Cfa, CFA synthase, cfaB, CFAS, CPS, CPS1, CPS2, CPS3, cyclopropane fatty acid synthase, cyclopropane fatty acid synthetase, cyclopropane fatty acyl synthase, cyclopropane synthase, cyclopropane-fatty-acyl-phospholipid synthase, HP0416, SfCPA-FAS, synthetase, cyclopropane fatty acid, unsaturated-phospholipid methyltransferase
ECTree
2.1.1.79 cyclopropane-fatty-acyl-phospholipid synthaseAdvanced search results
results (
results (Reference
top
Reference on EC 2.1.1.79 - cyclopropane-fatty-acyl-phospholipid synthase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Zalkin, H.; Law, J.H.; Goldfine, H.
Enzymic synthesis of cyclopropane fatty acids catalyzed by bacterial extracts
J. Biol. Chem.
238
1242-1248
1963
Clostridium butyricum, Serratia marcescens
Chung, A.E.; Law, J.H.
Cyclopropane fatty acid synthetase: partial purification and properties
Biochemistry
3
967-974
1964
Clostridium butyricum
Taylor, F.R.; Grogan, D.W.; Cronan, J.E.
Cyclopropane fatty acid synthase from Escherichia coli
Methods Enzymol.
71
133-139
1981
Escherichia coli, Escherichia coli B / ATCC 11303
Wang, A.Y.; Grogan, D.W.; Cronan, J.E.
Cyclopropane fatty acid synthase of Escherichia coli: deduced amino acid sequence, purification, and studies of the enzyme active site
Biochemistry
31
11020-11028
1992
Escherichia coli
Grogan, D.W.; Cronan, J.E.
Cloning and manipulation of the Escherichia coli cyclopropane fatty acid synthase gene: physiological aspects of enzyme overproduction
J. Bacteriol.
158
286-295
1984
Escherichia coli
Smith, D.D.; Norton, S.J.
Inhibition of cyclopropane fatty acid synthase by sinefungin and A9145C
Biochem. Biophys. Res. Commun.
94
1458-1462
1980
Lactiplantibacillus plantarum
Smith, D.D.; Norton, S.J.
S-Adenosylmethionine, cyclopropane fatty acid synthase, and the production of lactobacillic acid in Lactobacillus plantarum
Arch. Biochem. Biophys.
205
564-570
1980
Lactiplantibacillus plantarum
Taylor, F.R.; Cronan, J.E.
Cyclopropane fatty acid synthase of Escherichia coli. Stabilization, purification, and interaction with phospholipid vesicles
Biochemistry
18
3292-3300
1979
Escherichia coli
Chang, Y.Y.; Eichel, J.; Cronan, J.E., Jr.
Metabolic instability of Escherichia coli cyclopropane fatty acid synthase is due to RpoH-dependent proteolysis
J. Bacteriol.
182
4288-4294
2000
Escherichia coli
Kuchta, T.; Russell, N.
Glycinebetaine stimulates, but NaCl inhibits, fatty acid biosynthesis in the moderately halophilic eubacterium HX
Arch. Microbiol.
161
234-238
1994
Eubacterium HX
-
Bao, X.; Katz, S.; Pollard, M.; Ohlrogge, J.
Carbocyclic fatty acids in plants: biochemical and molecular genetic characterization of cyclopropane fatty acid synthesis of Sterculia foetida
Proc. Natl. Acad. Sci. USA
99
7172-7177
2002
Sterculia foetida
Bao, X.; Thelen, J.J.; Bonaventure, G.; Ohlrogge, J.B.
Characterization of cyclopropane fatty acid synthase from Sterculia foetida
J. Biol. Chem.
31
1-36
2003
Sterculia foetida
-
Iwig, D.F.; Grippe, A.T.; McIntyre, T.A.; Booker, S.J.
Isotope and elemental effects indicate a rate-limiting methyl transfer as the initial step in the reaction catalyzed by Escherichia coli cyclopropane fatty acid synthase
Biochemistry
43
13510-13524
2004
Escherichia coli
Molitor, E.J.; Paschal, B.M.; Liu, H.w.
Cyclopropane fatty acid synthase from Escherichia coli: Enzyme purification and inhibition by vinylfluorine and epoxide-containing substrate analogues
ChemBioChem
4
1352-1356
2003
Escherichia coli
Courtois, F.; Guerard, C.; Thomas, X.; Ploux, O.
Escherichia coli cyclopropane fatty acid synthase
Eur. J. Biochem.
271
4769-4778
2004
Escherichia coli
Kim, B.H.; Kim, S.; Kim, H.G.; Lee, J.; Lee, I.S.; Park, Y.K.
The formation of cyclopropane fatty acids in Salmonella enterica serovar Typhimurium
Microbiology
151
209-218
2005
Salmonella enterica
Munoz-Rojas, J.; Bernal, P.; Duque, E.; Godoy, P.; Segura, A.; Ramos, J.L.
Involvement of cyclopropane fatty acids in the response of Pseudomonas putida KT2440 to freeze-drying
Appl. Environ. Microbiol.
72
472-477
2006
Pseudomonas putida, Pseudomonas putida KT 2240
Courtois, F.; Ploux, O.
Escherichia coli cyclopropane fatty acid synthase: is a bound bicarbonate ion the active-site base?
Biochemistry
44
13583-13590
2005
Escherichia coli
Guianvarch, D.; Drujon, T.; Leang, T.E.; Courtois, F.; Ploux, O.
Identification of new inhibitors of E. coli cyclopropane fatty acid synthase using a colorimetric assay
Biochim. Biophys. Acta
1764
1381-1388
2006
Escherichia coli
Budin-Verneuil, A.; Maguin, E.; Auffray, Y.; Ehrlich, S.D.; Pichereau, V.
Transcriptional analysis of the cyclopropane fatty acid synthase gene of Lactococcus lactis MG1363 at low pH
FEMS Microbiol. Lett.
250
189-194
2005
Lactococcus lactis, Lactococcus lactis MG1363
Iwig, D.F.; Uchida, A.; Stromberg, J.A.; Booker, S.J.
The activity of Escherichia coli cyclopropane fatty acid synthase depends on the presence of bicarbonate
J. Am. Chem. Soc.
127
11612-11613
2005
Escherichia coli
Guianvarch, D.; Guangqi E, D.; Drujon, T.; Rey, C.; Wang, Q.; Ploux, O.
Identification of inhibitors of the E. coli cyclopropane fatty acid synthase from the screening of a chemical library: In vitro and in vivo studies
Biochim. Biophys. Acta
1784
1652-1658
2008
Escherichia coli
Grandvalet, C.; Assad-Garcia, J.S.; Chu-Ky, S.; Tollot, M.; Guzzo, J.; Gresti, J.; Tourdot-Marechal, R.
Changes in membrane lipid composition in ethanol- and acid-adapted Oenococcus oeni cells: characterization of the cfa gene by heterologous complementation
Microbiology
154
2611-2619
2008
Oenococcus oeni
Saborido Basconcillo, L.; Zaheer, R.; Finan, T.M.; McCarry, B.E.
Cyclopropane fatty acyl synthase in Sinorhizobium meliloti
Microbiology
155
373-385
2009
Sinorhizobium meliloti, Sinorhizobium meliloti RmP110
Rosenthal, A.Z.; Kim, Y.; Gralla, J.D.
Regulation of transcription by acetate in Escherichia coli: in vivo and in vitro comparisons
Mol. Microbiol.
68
907-917
2008
Escherichia coli
Guangqi, E.; Lesage, D.; Ploux, O.
Insight into the reaction mechanism of the Escherichia coli cyclopropane fatty acid synthase: isotope exchange and kinetic isotope effects
Biochimie
92
1454-1457
2010
Escherichia coli
Yu, X.H.; Rawat, R.; Shanklin, J.
Characterization and analysis of the cotton cyclopropane fatty acid synthase family and their contribution to cyclopropane fatty acid synthesis
BMC Plant Biol.
11
97
2011
Gossypium hirsutum
Jones, S.E.; Whitehead, K.; Saulnier, D.; Thomas, C.M.; Versalovic, J.; Britton, R.A.
Cyclopropane fatty acid synthase mutants of probiotic human-derived Lactobacillus reuteri are defective in TNF inhibition
Gut Microbes
2
69-79
2011
Limosilactobacillus reuteri, Limosilactobacillus reuteri ATCC PTA 6475
Palacios-Chaves, L.; Zuniga-Ripa, A.; Gutierrez, A.; Gil-Ramirez, Y.; Conde-Alvarez, R.; Moriyon, I.; Iriarte, M.
Identification and functional analysis of the cyclopropane fatty acid synthase of Brucella abortus
Microbiology
158
1037-1044
2012
Brucella abortus, Brucella abortus 2308 NalR
To, T.M.; Grandvalet, C.; Alexandre, H.; Tourdot-Marechal, R.
Cyclopropane fatty acid synthase from Oenococcus oeni: expression in Lactococcus lactis subsp. cremoris and biochemical characterization
Arch. Microbiol.
197
1063-1074
2015
Oenococcus oeni
E, G.; Drujon, T.; Correia, I.; Ploux, O.; Guianvarch, D.
An active site mutant of Escherichia coli cyclopropane fatty acid synthase forms new non-natural fatty acids providing insights on the mechanism of the enzymatic reaction
Biochimie
95
2336-2344
2013
Escherichia coli, Escherichia coli (P0A9H7)
Broadbent, J.R.; Oberg, T.S.; Hughes, J.E.; Ward, R.E.; Brighton, C.; Welker, D.L.; Steele, J.L.
Influence of polysorbate 80 and cyclopropane fatty acid synthase activity on lactic acid production by Lactobacillus casei ATCC 334 at low pH
J. Ind. Microbiol. Biotechnol.
41
545-553
2014
Lacticaseibacillus casei, Lacticaseibacillus casei ATCC 334
Yu, X.H.; Prakash, R.R.; Sweet, M.; Shanklin, J.
Coexpressing Escherichia coli cyclopropane synthase with Sterculia foetida lysophosphatidic acid acyltransferase enhances cyclopropane fatty acid accumulation
Plant Physiol.
164
455-465
2014
Escherichia coli
Oyola, S.O.; Evans, K.J.; Smith, T.K.; Smith, B.A.; Hilley, J.D.; Mottram, J.C.; Kaye, P.M.; Smith, D.F.
Functional analysis of Leishmania cyclopropane fatty acid synthetase
PLoS ONE
7
e51300
2012
Leishmania infantum
Peng, H.; He, L.; Haritos, V.S.
Enhanced production of high-value cyclopropane fatty acid in yeast engineered for increased lipid synthesis and accumulation
Biotechnol. J.
14
e1800487
2019
Escherichia coli (P0A9H7), Escherichia coli
Xu, W.; Mukherjee, S.; Ning, Y.; Hsu, F.F.; Zhang, K.
Cyclopropane fatty acid synthesis affects cell shape and acid resistance in Leishmania mexicana
Int. J. Parasitol.
48
245-256
2018
Leishmania mexicana, Leishmania mexicana M379
Jiang, X.; Duan, Y.; Zhou, B.; Guo, Q.; Wang, H.; Hang, X.; Zeng, L.; Jia, J.; Bi, H.
The cyclopropane fatty acid synthase mediates antibiotic resistance and gastric colonization of Helicobacter pylori
J. Bacteriol.
201
e00374-19
2019
Helicobacter pylori, Helicobacter pylori 26695
html completed
