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2.1.1.76: quercetin 3-O-methyltransferase

This is an abbreviated version!
For detailed information about quercetin 3-O-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.76

Reaction

S-adenosyl-L-methionine
+
3,5,7,3',4'-pentahydroxyflavone
=
S-adenosyl-L-homocysteine
+
3-methoxy-5,7,3',4'-tetrahydroxyflavone

Synonyms

3-OMT, CdFOMT5, flavonoid 3-methyltransferase, flavonoid-O-methyltransferase, flavonol 3-O-methyltransferase, FOMT5, Mg2+-independent O-methyltransferase, MOMT3, More, quercetin 3-O-methyltransferase 1, S-adenosyl-L-methionine:quercetin 3-O-methyltransferase, trimethylfavonol 3'/5'-OMT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.76 quercetin 3-O-methyltransferase

Natural Substrates Products

Natural Substrates Products on EC 2.1.1.76 - quercetin 3-O-methyltransferase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
4 S-adenosyl-L-methionine + quercetin
4 S-adenosyl-L-homocysteine + 3,3',5,7-tetramethoxyquercetin
show the reaction diagram
whole-cell biocatalysis using CdFOMT5 expressed in Escherichia coli cells is performed using quercetin as a substrate, and 3,3',5,7-tetramethylated quercetin is obtained as the final product
-
-
?
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone
S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone
show the reaction diagram
additional information
?
-
-
the enzyme does not methylate 3',4',5'-O-trimethylmyricetin, 3,7,3',4'-O-methylquercetin, 3-methylquercetin, and 3,7,4'-O-trimethylkaempferol. The enzyme transfers a methyl group only to the 3-position hydroxyl
-
-
?