2.1.1.74: methylenetetrahydrofolate-tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]

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For detailed information about methylenetetrahydrofolate-tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing], go to the full flat file.

Word Map on EC 2.1.1.74

2.1.1.74

flavin

m5u54-methyltransferase

5-methyluridine

s-adenosyl-l-methionine

medicine

methyltransferases

t-arms

ribothymidine

t-loops

flavin-dependent

n5,n10-methylenetetrahydrofolate

ch2thf

t-stem

isoalloxazine

ultrafast

Reaction

Synonyms

EC 2.1.2.12, FDRTS, folate-dependent ribothymidyl synthase, folate-dependent tRNA methyltransferase, folate/FAD-dependent tRNA T54 methyltransferase, methylenetetrahydrofolate-transfer ribonucleate uracil 5-methyltransferase,, TRMFO, tRNA (m5U54)-methyltransferase, tRNA:m5U-54 MTase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.74 methylenetetrahydrofolate-tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]

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Results	in table
11291	AA Sequence
8	Application
1	CAS Registry Number
5	Cloned(Commentary)
19	Cofactor
2	Crystallization (Commentary)
1	General Information
1	General Stability
11	KM Value [mM]
1	Localization
2	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
25	Organism
3	PDB ID
5	pH Optimum
17	Protein Variants
6	Purification (Commentary)
2	Reaction
2	Reaction Type
25	Reference
2	Specific Activity [micromol/min/mg]
45	Substrates and Products (Substrate)
33	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]

Natural Substrates Products

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Natural Substrates Products on EC 2.1.1.74 - methylenetetrahydrofolate-tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]

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5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH2

tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD

2 entries

5,10-methylenetetrahydrofolate + tRNA UpsiC + FADH2

tetrahydrofolate + tRNA TpsiC + FAD

7 entries