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2.1.1.61: tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase

This is an abbreviated version!
For detailed information about tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.61

Reaction

S-adenosyl-L-methionine
+
5-aminomehtyl-2-thiouridine34 in tRNALys
=
S-adenosyl-L-homocysteine
+
5-methylaminomehtyl-2-thiouridine34 in tRNALys

Synonyms

5-methylaminomethyl-2-thiouridylate methyltransferase, 5-methylaminomethyl-2-thiouridylate-methyltransferase, methylaminomethyl-2-thiouridylate-methyltransferase, methyltransferase, transfer ribonucleate 5-methylaminomethyl-2-thiouridylate 5-, MTO2, MTU1, S-adenosyl-L-methionine:tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase, transfer ribonucleate 5-methylaminomethyl-2-thiouridylate 5-methyltransferase, TRMU, tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase, tRNA 5-methylaminomethyl-2-thiouridylate 5'-methyltransferase, tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.61 tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase

Engineering

Engineering on EC 2.1.1.61 - tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
G14S
-
the mutation is associated with acute liver failure in infancy
G272D
-
the mutation is associated with acute liver failure in infancy
L233F/A10S
-
the mutation is associated with acute liver failure in infancy
M1K
-
the mutation is associated with acute liver failure in infancy
V279M
-
the mutation is associated with acute liver failure in infancy
Y77H
-
the mutation is associated with acute liver failure in infancy