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2.1.1.6: catechol O-methyltransferase

This is an abbreviated version!
For detailed information about catechol O-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.6

Reaction

S-adenosyl-L-methionine
+
a catechol
=
S-adenosyl-L-homocysteine
+
a guaiacol

Synonyms

catechol methyltransferase, catechol-O-methyl transferase, catechol-O-methyl transferase, membrane bound, catechol-O-methyl transferase, soluble, catechol-O-methyltransferase, catechol-O-transferase, catecholamine O-methyltransferase, COMT, COMT I, COMT II, COMT-mb, COMT-s, COMT1, COMT2, CTOMT1, L-COMT, MB-COMT, methyltransferase, catechol, S-COMT, SCOMT

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.6 catechol O-methyltransferase

Molecular Weight

Molecular Weight on EC 2.1.1.6 - catechol O-methyltransferase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
21000
-
gel filtration
23000
24000
24300
-
S-COMT
24889
1 * 24889, ESI Q-pole mass spectrometry
24890
24891
1 * 24891, calculated from amino acid sequence
25000
25000 - 26000
-
gel filtration, SDS-PAGE
25700
-
1 * 25700, liver, SDS-PAGE
27500
-
-
28000
29000
-
x * 29000, hepatoma cell line G2, SDS-PAGE
30000
32000
36000
-
gel filtration
47500
-
COMT II, gel filtration, sedimentation data