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2.1.1.5: betaine-homocysteine S-methyltransferase

This is an abbreviated version!
For detailed information about betaine-homocysteine S-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.5

Reaction

betaine
+
L-homocysteine
=
dimethylglycine
+
L-methionine

Synonyms

betaine homocysteine methyltransferase, betaine homocysteine methyltransferase-1, betaine homocysteine S-methyltransferase, betaine-homocysteine methyltransferase, betaine-homocysteine S-methyltransferase, betaine-homocysteine S-methyltransferase 2, betaine-homocysteine S-methyltransferase-2, betaine-homocysteine transmethylase, betaine:homocysteine methyltransferase, betaine:homocysteine S-methyltransferase, BHMT, BHMT-1, BHMT-2, BHMT1, BHMT2, methyltransferase, betaine-homocysteine

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.5 betaine-homocysteine S-methyltransferase

IC50 Value

IC50 Value on EC 2.1.1.5 - betaine-homocysteine S-methyltransferase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.000096
(R,S)-2-amino-4-(2-carboxymethylsulfanyl-ethylsulfanyl)-butyric acid
Homo sapiens
-
-
0.0057
(R,S)-2-amino-4-(4-phosphono-butylsulfanyl)-butyric acid
Homo sapiens
-
-
0.007
(R,S)-4-(3-amino-3-carboxy-propylsulfanyl)-benzoic acid
Homo sapiens
-
-
0.000087
(R,S)-5-(3-amino-3-carboxy-propylsulfanyl)-pentanoic acid
Homo sapiens
-
-
0.005
(R,S)-5-(3-amino-3-carboxy-propylsulfinyl)-pentanoic acid
Homo sapiens
-
-
0.0002
(R,S)-6-(3-amino-3-carboxy-propylsulfanyl)-hexanoic acid
Homo sapiens
-
-
0.00326
(RS)-2-amino-4-[(2-carboxyethylthio)methylthio]butanoic acid
Homo sapiens
-
in 50 mM potassium phosphate buffer, at pH 7.5, at 37°C
0.0025
(RS)-2-amino-4-[2-[(carboxymethyl)(methyl)amino]ethylthio]-butanoic acid
Homo sapiens
-
in 50 mM potassium phosphate buffer, at pH 7.5, at 37°C
0.000649
(RS)-5-(3-amino-3-carboxypropylselanyl)pentanoic acid
Homo sapiens
-
in 50 mM potassium phosphate buffer, at pH 7.5, at 37°C
0.000084
(RS)-5-(3-amino-3-carboxypropylthio)-3,3-dimethylpentanoic acid
Homo sapiens
-
in 50 mM potassium phosphate buffer, at pH 7.5, at 37°C
0.000139
(RS)-5-(3-amino-3-carboxypropylthio)-3-methylpentanoic acid
Homo sapiens
-
in 50 mM potassium phosphate buffer, at pH 7.5, at 37°C
0.000093
5-(3-amino-3-carboxy-propylsulfanyl)-pentanoic acid
Homo sapiens
pH not specified in the publication, temperature not specified in the publication
0.0011
5-[3-(R,S)-3-amino-3-(hydroxyphosphorylpropyl)sulfanyl]-3,3-dimethylpentanoic acid
Homo sapiens
pH not specified in the publication, temperature not specified in the publication
0.005
5-[3-(R,S)-3-amino-3-(hydroxyphosphorylpropyl)sulfanyl]pentanoic acid
Homo sapiens
pH not specified in the publication, temperature not specified in the publication