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2.1.1.49: amine N-methyltransferase

This is an abbreviated version!
For detailed information about amine N-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.49

Reaction

S-adenosyl-L-methionine
+
an amine
=
S-adenosyl-L-homocysteine
+
a methylated amine

Synonyms

aromatic alkylamine-N-methyltransferase, arylamine N-methyltransferase, EC 2.1.1.81, methyltransferase, tryptamine, nicotine N-methyltransferase, tryptamine methyltransferase, tryptamine N-methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.49 amine N-methyltransferase

Systematic Name

Systematic Name on EC 2.1.1.49 - amine N-methyltransferase

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SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:amine N-methyltransferase
An enzyme of very broad specificity; many primary, secondary and tertiary amines can act as acceptors, including tryptamine, aniline, nicotine and a variety of drugs and other xenobiotics.