2.1.1.33: tRNA (guanine46-N7)-methyltransferase

This is an abbreviated version!
For detailed information about tRNA (guanine46-N7)-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.33

2.1.1.33

methyltransferase-like

n7-methylguanosine

cyp27b1

mettl21b

trnaphe

mescs

kidney-specific

methylome

submodules

methyl-transfer

pharmacology

Reaction

Synonyms

7-methylguanine transfer ribonucleate methylase, m7G-methyltransferase, m7G46 methyltransferase Trm8p/Trm82p, methyltransferase like 1, methyltransferase, transfer ribonucleate guanine 7-, METTL1, N7-methylguanine methylase, PA14_05000, transfer ribonucleate guanine 7-methyltransferase, transfer RNA (m7G46) methyltransferase, Trm8�Trm82 complex, TrmB, TrMet (m7G46), tRNA (m7G46) methyltransferase, tRNA guanine 7-methyltransferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.33 tRNA (guanine46-N7)-methyltransferase

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Results	in table
6	Activating Compound
34950	AA Sequence
1	Application
1	CAS Registry Number
5	Cloned(Commentary)
11	Cofactor
2	Crystallization (Commentary)
39	Disease/ Diagnostics
15	General Information
2	General Stability
12	Inhibitors
5	Ki Value [mM]
26	KM Value [mM]
7	Localization
6	Metals/Ions
6	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
51	Organism
25	PDB ID
2	pH Optimum
1	Posttranslational Modification
22	Protein Variants
13	Purification (Commentary)
2	Reaction
1	Reaction Type
25	Reference
2	Source Tissue
1	Specific Activity [micromol/min/mg]
3	Storage Stability
62	Substrates and Products (Substrate)
5	Subunits
25	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]

Molecular Weight

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Molecular Weight on EC 2.1.1.33 - tRNA (guanine46-N7)-methyltransferase

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100000

Escherichia coli

gel filtration, two m7G tRNA-methyltransferases with different specificities for the extra arm unpaired G in different tRNA species

441474

25000

Salmonella enterica subsp. enterica serovar Typhimurium

glycerol gradient centrifugation

441341

27307

Escherichia coli

P0A8I5

x * 27307, calculated from sequence

701560

300000

Escherichia coli

gel filtration, two m7G tRNA-methyltransferases with different specificities for the extra arm unpaired G in different tRNA species

441474

33000

Saccharomyces cerevisiae

1 * 33000 (subunit Trm8) + 1 * 50000 (subunit Trm82), association of the Trm8 and Trm82 subunits is translationally controlled in living cells, SDS-PAGE

704753

50000

Saccharomyces cerevisiae

1 * 33000 (subunit Trm8) + 1 * 50000 (subunit Trm82), association of the Trm8 and Trm82 subunits is translationally controlled in living cells, SDS-PAGE

704753