2.1.1.20: glycine N-methyltransferase

This is an abbreviated version!
For detailed information about glycine N-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.20

2.1.1.20

s-adenosylmethionine

s-adenosylhomocysteine

homocysteine

folate

sarcosine

adenosyltransferase

cystathionine

transmethylation

adomet

betaine-homocysteine

remethylation

beta-synthase

one-carbon

transsulfuration

5-methyltetrahydrofolate

medicine

folate-dependent

n-methylglycine

s-methyltransferase

glycine-n-methyltransferase

guanidinoacetate

folate-deficient

pentaglutamate

pah-binding

adohcy

diagnostics

Reaction

Synonyms

4S polycyclic aromatic hydrocarbon binding protein, glycine methyltransferase, glycine N-methyltransferase, glycine-N methyltransferase, GNMT, Gnmt gene product, methyltransferase, glycine, S-adenosyl-L-methionine:glycine methyltransferase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.20 glycine N-methyltransferase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
14	Activating Compound
1116	AA Sequence
16	Application
1	CAS Registry Number
30	Cloned(Commentary)
13	Crystallization (Commentary)
611	Disease/ Diagnostics
8	Expression
24	General Information
1	General Stability
4	IC50 Value
56	Inhibitors
14	kcat/KM [mM/s]
8	Ki Value [mM]
40	KM Value [mM]
36	Localization
36	Molecular Weight [Da]
22	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
78	Organism
6	Pathway
44	PDB ID
11	pH Optimum
1	pH Range
3	pI Value
6	Posttranslational Modification
26	Protein Variants
19	Purification (Commentary)
11	Reaction
1	Reaction Type
77	Reference
139	Source Tissue
4	Specific Activity [micromol/min/mg]
3	Storage Stability
65	Substrates and Products (Substrate)
21	Subunits
60	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
27	Turnover Number [1/s]

Expression

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Expression on EC 2.1.1.20 - glycine N-methyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Expression Search

benzo[a]pyrene treatment of HepG2 cells (0.001 or 0.01 mM) induces GNMT expression

Homo sapiens

703849

GNMT expression is down-regulated or even completely blocked in liver and prostate tumor tissue

6 entries

GNMT expression is stimulated by androgen in androgen receptor expressing cells, the stimulation occurs at the mRNA and protein levels. Androgen receptor binds to an androgen response element within the first exon of the GNMT gene in vitro and in vivo

Homo sapiens

734506