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2.1.1.13: methionine synthase

This is an abbreviated version!
For detailed information about methionine synthase, go to the full flat file.

Word Map on EC 2.1.1.13

Reaction

5-methyltetrahydrofolate
+
L-homocysteine
=
tetrahydrofolate
+
L-methionine

Synonyms

5-methyltetrahydrofolate homocysteine methyltransferase, 5-methyltetrahydrofolate-homocysteine methyltransferase, 5-methyltetrahydrofolate-homocysteine S-methyltransferase, 5-methyltetrahydrofolate-homocysteine transmethylase, B12 N5-methyltetrahydrofolate homocysteine methyltransferase, B12-dependent methionine synthase, cobalamin-dependent methionine synthase, folate-dependent methionine synthase, Met6p, MetH, methionine synthase, methionine synthetase, methyltetrahydrofolate-homocysteine vitamin B12 methyltransferase, methyltransferase, methyltetrahydrofolate-homocysteine, MetS, MS, MS1, MTR, N-methyltetrahydrofolate:L-homocysteine methyltransferase, N5-methyltetrahydrofolate methyltransferase, N5-methyltetrahydrofolate-homocysteine cobalamin methyltransferase, N5-methyltetrahydrofolic-homocysteine vitamin B12 transmethylase, tetrahydrofolate methyltransferase, tetrahydropteroylglutamate methyltransferase, tetrahydropteroylglutamic methyltransferase, vitamin B12 methyltransferase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.13 methionine synthase

Molecular Weight

Molecular Weight on EC 2.1.1.13 - methionine synthase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
112000
-
GST fusion protein, SDS-PAGE
133000
-
x * 133000, SDS-PAGE
140000
140000 - 150000
-
gel filtration, sedimentation coefficient in sucrose density gradients
150000
-
gel filtration
151000
-
1 * 151000, SDS-PAGE
151000 - 155000
-
gel filtration
153000
-
gel filtration
160000
-
gel filtration
186000
-
gel filtration
200000
-
gel filtration
35000
-
x * 90000 + x * 45000 + x * 35000, SDS-PAGE of reduced enzyme
36200
-
sedimentation in high salt buffer
40000
43100
-
1 * 43100, light scattering
45000
-
x * 90000 + x * 45000 + x * 35000, SDS-PAGE of reduced enzyme
49500
-
x * 49500, 2 different types of subunits, SDS-PAGE
86000
-
SDS-PAGE
90000
-
x * 90000 + x * 45000 + x * 35000, SDS-PAGE of reduced enzyme