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2.1.1.104: caffeoyl-CoA O-methyltransferase

This is an abbreviated version!
For detailed information about caffeoyl-CoA O-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.104

Reaction

S-adenosyl-L-methionine
+
caffeoyl-CoA
=
S-adenosyl-L-homocysteine
+
feruloyl-CoA

Synonyms

ASCCoAOMT, At4g26220, caffeic acid 3-O-methyltransferase, caffeoyl CoA 3-O-methyltransferase, caffeoyl CoA methyltransferase, caffeoyl CoA methyltransferase 7, caffeoyl CoA O-methyltransferase, caffeoyl CoA-O-methyltransferase, caffeoyl coenzyme A 3-O-methyltransferase, caffeoyl coenzyme A methyltransferase, caffeoyl coenzyme A O-methyltransferase, caffeoyl-CoA 3-O-methyltransferase, caffeoyl-CoA-O-methyl transferase 1, caffeoyl-CoA-O-methyl transferase 2, caffeoyl-coenzyme A 3-o-methyltransferase, caffeoyl-coenzyme A O-methyltransferase, CCoAMT, CCoAOMT, CCoAOMT 1, CCoAOMT 2, CCoAOMT-1, CCoAOMT-like, CCoAOMT1, CCoAOMT2, CCoAOMT7, CCOMT, COMT, F6OMT, hi12, More, O-methyltransferase, OMT-15, OMT-17, OMT1, S-adenosyl-L-methionine:trans-caffeoyl-CoA 3-O-methyltransferase, TaCCoAOMT1, trans-caffeoyl-CoA 3-O-methyltransferase, Vp-OMT4, Vp-OMT5

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.104 caffeoyl-CoA O-methyltransferase

Reference

Reference on EC 2.1.1.104 - caffeoyl-CoA O-methyltransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Marita, J.M.; Ralph, J.; Hatfield, R.D.; Guo, D.; Chen, F.; Dixon, R.A.
Structural and compositional modifications in lignin of transgenic alfalfa down-regulated in caffeic acid 3-O-methyltransferase and caffeoyl coenzyme A 3-O-methyltransferase
Phytochemistry
62
53-65
2003
Medicago sativa
Manually annotated by BRENDA team
Day, A.; Dehorter, B.; Neutelings, G.; Czeszak, X.; Chabbert, B.; Belingheri, L.; David, H.
Caffeoyl-coenzyme A 3-O-methyltransferase enzyme activity, protein and transcript accumulation in flax (Linum usitatissimum) stem during development
Physiol. Plant.
113
275-284
2001
Linum usitatissimum
Manually annotated by BRENDA team
Hoffmann, L.; Maury, S.; Bergdoll, M.; Thion, L.; Erard, M.; Legrand, M.
Identification of the enzymatic active site of tobacco caffeoyl-coenzyme A O-methyltransferase by site-directed mutagenesis
J. Biol. Chem.
276
36831-36838
2001
Nicotiana tabacum
Manually annotated by BRENDA team
Parvathi, K.; Chen, F.; Guo, D.; Blount, J.W.; Dixon, R.A.
Substrate preferences of O-methyltransferases in alfalfa suggest new pathways for 3-O-methylation of monolignols
Plant J.
25
193-202
2001
Medicago sativa
Manually annotated by BRENDA team
Zhong, R.; Morrison, W.H.; Himmelsbach, D.S.; Poole, F.L.; Ye, Z.H.
Essential role of caffeoyl coenzyme A O-methyltransferase in lignin biosynthesis in woody poplar plants
Plant Physiol.
124
563-578
2000
Populus tremula x Populus alba (Q43095)
Manually annotated by BRENDA team
Chen, C.; Meyermans, H.; Burggraeve, B.; De Rycke, R.M.; Inoue, K.; De Vleesschauwer, V.; Steenackers, M.; Van Montagu, M.C.; Engler, G.J.; Boerjan, W.A.
Cell-specific and conditional expression of caffeoyl-coenzyme A-3-O-methyltransferase in poplar
Plant Physiol.
123
853-867
2000
Populus tremula x Populus alba, Populus trichocarpa
Manually annotated by BRENDA team
Maury, S.; Geoffroy, P.; Legrand, M.
Tobacco O-methyltransferases involved in phenylpropanoid metabolism. The different caffeoyl-coenzyme A/5-hydroxyferuloyl-coenzyme A 3/5-O-methyltransferase and caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase classes have distinct substrate specificities and expression patterns
Plant Physiol.
121
215-224
1999
Nicotiana tabacum
Manually annotated by BRENDA team
Grimmig, B.; Kneusel, R.E.; Junghanns, K.T.; Matern, U.
Expression of bifunctional caffeoyl-CoA 3-O-methyltransferase in stress compensation and lignification
Plant Biol.
1
299-310
1999
Nicotiana tabacum, Petroselinum crispum
-
Manually annotated by BRENDA team
Martz, F.; Maury, S.; Pincon, G.; Legrand, M.
cDNA cloning, substrate specificity and expression study of tobacco caffeoyl-CoA 3-O-methyltransferase, a lignin biosynthetic enzyme
Plant Mol. Biol.
36
427-437
1998
Nicotiana tabacum
Manually annotated by BRENDA team
Meng, H.; Campbell, W.H.
Substrate profiles and expression of caffeoyl coenzyme A and caffeic acid O-methyltransferases in secondary xylem of aspen during seasonal development
Plant Mol. Biol.
38
513-520
1998
Populus tremuloides
Manually annotated by BRENDA team
Inoue, K.; Sewalt, V.J.H.; Ballance, G.M.; Ni, W.; Sturzer, C.; Dixon, R.A.
Developmental expression and substrate specificities of alfalfa caffeic acid 3-O-methyltransferase and caffeoyl coenzyme A 3-O-methyltransferase in relation to lignification
Plant Physiol.
117
761-770
1998
Medicago sativa (Q40313), Medicago sativa
Manually annotated by BRENDA team
Busam, G.; Junghanns, K.T.; Kneusel, R.E.; Kassemeyer, H.H.; Matern, U.
Characterization and expression of caffeoyl-coenzyme A 3-O-methyltransferase proposed for the induced resistance response of Vitis vinifera L
Plant Physiol.
115
1039-1048
1997
Vitis vinifera
Manually annotated by BRENDA team
Ni, W.; Sewalt, V.J.H.; Korth, K.L.; Blount, J.W.; Ballance, G.M.; Dixon, R.A.
Stress responses in alfalfa. XXI. Activation of caffeic acid 3-O-methyltransferase and caffeoyl coenzyme A 3-O-methyltransferase genes does not contribute to changes in metabolite accumulation in elicitor-treated cell-suspension cultures
Plant Physiol.
112
717-726
1996
Medicago sativa
Manually annotated by BRENDA team
Pakusch, A.E.; Matern, U.; Schiltz, E.
Elicitor-inducible caffeoyl-coenzyme A 3-O-methyltransferase from Petroselinum crispum cell suspensions
Plant Physiol.
95
137-143
1991
Petroselinum crispum
Manually annotated by BRENDA team
Pakusch, A.E.; Matern, U.
Kinetic characterization of caffeoyl-coenzyme A-specific 3-O-methyltransferase from elicited parsley cell suspensions
Plant Physiol.
96
327-330
1991
Petroselinum crispum
Manually annotated by BRENDA team
Schmidt, D.; Pakusch, A.E.; Matern, U.
Molecular cloning, induction and taxonomic distribution of caffeoyl-CoA 3-O-methyltransferase, an enzyme involved in disease resistance
J. Biol. Chem.
266
17416-17423
1991
Ammi majus, Carthamus tinctorius, Daucus carota, Dianthus caryophyllus, Petroselinum crispum
Manually annotated by BRENDA team
Pakusch, A.E.; Kneusel, R.E.; Matern, U.
S-Adenosyl-L-methionine:trans-caffeoyl-coenzyme A 3-O-methyltransferase from elicitor-treated parsley cell suspension cultures
Arch. Biochem. Biophys.
271
488-494
1989
Petroselinum crispum
Manually annotated by BRENDA team
Ye, Z.H.; Zhong, R.; Morrison, W.H.; Himmelsbach, D.S.
Caffeoyl coenzyme A O-methyltransferase and lignin biosynthesis
Phytochemistry
57
1177-1185
2001
Zinnia sp.
Manually annotated by BRENDA team
Vincent, D.; Lapierre, C.; Pollet, B.; Cornic, G.; Negroni, L.; Zivy, M.
Water deficits affect caffeate O-methyltransferase, lignification, and related enzymes in maize leaves. A proteomic investigation
Plant Physiol.
137
949-960
2005
Zea mays
Manually annotated by BRENDA team
Lukacin, R.; Matern, U.; Specker, S.; Vogt, T.
Cations modulate the substrate specificity of bifunctional class I O-methyltransferase from Ammi majus
FEBS Lett.
577
367-370
2004
Ammi majus
Manually annotated by BRENDA team
Yang, Q.; Trinh, H.X.; Imai, S.; Ishihara, A.; Zhang, L.; Nakayashiki, H.; Tosa, Y.; Mayama, S.
Analysis of the involvement of hydroxyanthranilate hydroxycinnamoyltransferase and caffeoyl-CoA 3-O-methyltransferase in phytoalexin biosynthesis in oat
Mol. Plant Microbe Interact.
17
81-89
2004
Avena sativa
Manually annotated by BRENDA team
Ferrer, J.L.; Zubieta, C.; Dixon, R.A.; Noel, J.P.
Crystal structures of alfalfa caffeoyl coenzyme A 3-O-methyltransferase
Plant Physiol.
137
1009-1017
2005
Medicago sativa, Medicago sativa (Q40313)
Manually annotated by BRENDA team
Imin, N.; Kerim, T.; Weinman, J.J.; Rolfe, B.G.
Low temperature treatment at the young microspore stage induces protein changes in rice anthers
Mol. Cell. Proteomics
5
274-292
2006
Oryza sativa (Q9XGP7), Oryza sativa
Manually annotated by BRENDA team
Ramirez-Ahumada, M.d.e.l.C.; Timmermann, B.N.; Gang, D.R.
Biosynthesis of curcuminoids and gingerols in turmeric (Curcuma longa) and ginger (Zingiber officinale): identification of curcuminoid synthase and hydroxycinnamoyl-CoA thioesterases
Phytochemistry
67
2017-2029
2006
Curcuma longa, Zingiber officinale
Manually annotated by BRENDA team
Li, L.; Cheng, X.; Lu, S.; Nakatsubo, T.; Umezawa, T.; Chiang, V.L.
Clarification of cinnamoyl co-enzyme A reductase catalysis in monolignol biosynthesis of Aspen
Plant Cell Physiol.
46
1073-1082
2005
Populus tremuloides
Manually annotated by BRENDA team
Chen, F.; Srinivasa Reddy, M.S.; Temple, S.; Jackson, L.; Shadle, G.; Dixon, R.A.
Multi-site genetic modulation of monolignol biosynthesis suggests new routes for formation of syringyl lignin and wall-bound ferulic acid in alfalfa (Medicago sativa L.)
Plant J.
48
113-124
2006
Medicago sativa
Manually annotated by BRENDA team
Do, C.T.; Pollet, B.; Thevenin, J.; Sibout, R.; Denoue, D.; Barriere, Y.; Lapierre, C.; Jouanin, L.
Both caffeoyl Coenzyme A 3-O-methyltransferase 1 and caffeic acid O-methyltransferase 1 are involved in redundant functions for lignin, flavonoids and sinapoyl malate biosynthesis in Arabidopsis
Planta
226
1117-1129
2007
Arabidopsis thaliana (O49499), Arabidopsis thaliana
Manually annotated by BRENDA team
Lee, Y.; Kim, B.; Chong, Y.; Lim, Y.; Ahn, J.
Cation dependent O-methyltransferases from rice
Planta
227
641-647
2008
Oryza sativa
Manually annotated by BRENDA team
Ma, Q.; Xu, Y.
Characterization of a caffeic acid 3-O-methyltransferase from wheat and its function in lignin biosynthesis
Biochimie
90
515-524
2008
Nicotiana tabacum (O24149), Nicotiana tabacum, Triticum aestivum (Q38J50), Triticum aestivum
Manually annotated by BRENDA team
Riboulet, C.; Guillaumie, S.; Mechin, V.; Bosio, M.; Pichon, M.; Goffner, D.; Lapierre, C.; Pollet, B.; Lefevre, B.; Martinant, J.; Barriere, Y.
Kinetics of phenylpropanoid gene expression in maize growing internodes: relationships with cell wall deposition
Crop Sci.
49
211-223
2009
Zea mays, Zea mays (Q9XGD5), Zea mays (Q9XGD6)
Manually annotated by BRENDA team
Sekhar Pagadala, N.; Arha, M.; Reddy, P.S.; Kumar, R.; Sirisha, V.L.; Prashant, S.; Janardhan Reddy, K.; Khan, B.; Rawal, S.K.; Kavi Kishor, P.B.
Phylogenetic analysis, homology modelling, molecular dynamics and docking studies of caffeoyl-CoA-O-methyl transferase (CCoAOMT 1 and 2) isoforms isolated from subabul (Leucaena leucocephala)
J. Mol. Model.
15
203-221
2009
Leucaena leucocephala (Q0N3X0), Leucaena leucocephala (Q0N3X1)
Manually annotated by BRENDA team
Miao, L.; Shou, S.; Zhu, Z.; Jiang, F.; Zai, W.; Yang, Y.
Isolation of a novel tomato caffeoyl CoA 3-O-methyltransferase gene following infection with the bacterium Ralstonia solanacearum
J. Phytopathol.
156
588-596
2008
Solanum peruvianum, Solanum lycopersicum (A8IFQ7)
-
Manually annotated by BRENDA team
Day, A.; Neutelings, G.; Nolin, F.; Grec, S.; Habrant, A.; Cronier, D.; Maher, B.; Rolando, C.; David, H.; Chabbert, B.; Hawkins, S.
Caffeoyl coenzyme A O-methyltransferase down-regulation is associated with modifications in lignin and cell-wall architecture in flax secondary xylem
Plant Physiol. Biochem.
47
9-19
2009
Linum usitatissimum (Q4JHB1), Linum usitatissimum
Manually annotated by BRENDA team
Phogat, N.; Vindal, V.; Kumar, V.; Inampudi, K.K.; Prasad, N.K.
Sequence analysis, in silico modeling and docking studies of caffeoyl CoA-O-methyltransferase of Populus trichopora
J. Mol. Model.
16
1461-1471
2010
Populus trichocarpa (O65862), Populus trichocarpa (O65922)
Manually annotated by BRENDA team
Widiez, T.; Hartman, T.G.; Dudai, N.; Yan, Q.; Lawton, M.; Havkin-Frenkel, D.; Belanger, F.C.
Functional characterization of two new members of the caffeoyl CoA O-methyltransferase-like gene family from Vanilla planifolia reveals a new class of plastid-localized O-methyltransferases
Plant Mol. Biol.
76
475-488
2011
Vanilla planifolia (F2YP45), Vanilla planifolia (F2YP46), Vanilla planifolia
Manually annotated by BRENDA team
Ghosh, R.; Choi, B.; Jeong, M.; Bae, D.; Shin, S.; Park, S.; Lim, H.; Kim, J.; Bae, H.
Comparative transcriptional analysis of caffeoyl-coenzyme A 3-O-methyltransferase from Hibiscus cannabinus L., during developmental stages in various tissues and stress regulation
Plant OMICS
5
184-193
2012
Hibiscus cannabinus (I6ZPR8)
-
Manually annotated by BRENDA team
Fellenberg, C.; van Ohlen, M.; Handrick, V.; Vogt, T.
The role of CCoAOMT1 and COMT1 in Arabidopsis anthers
Planta
236
51-61
2012
Arabidopsis thaliana (O49499)
Manually annotated by BRENDA team
Naaz, H.; Pandey, V.P.; Singh, S.; Dwivedi, U.N.
Structure-function analyses and molecular modeling of caffeic acid-O-methyltransferase and caffeoyl-CoA-O-methyltransferase: revisiting the basis of alternate methylation pathways during monolignol biosynthesis
Biotechnol. Appl. Biochem.
60
170-189
2013
Medicago sativa (Q40313), Medicago sativa
Manually annotated by BRENDA team
Wils, C.R.; Brandt, W.; Manke, K.; Vogt, T.
A single amino acid determines position specificity of an Arabidopsis thaliana CCoAOMT-like O-methyltransferase
FEBS Lett.
587
683-689
2013
Arabidopsis thaliana (Q9C5D7), Arabidopsis thaliana
Manually annotated by BRENDA team
Li, X.; Chen, W.; Zhao, Y.; Xiang, Y.; Jiang, H.; Zhu, S.; Cheng, B.
Downregulation of caffeoyl-CoA O-methyltransferase (CCoAOMT) by RNA interference leads to reduced lignin production in maize straw
Genet. Mol. Biol.
36
540-546
2013
Zea mays (Q5GLK6), Zea mays
Manually annotated by BRENDA team
Zhang, Y.; Lv, H.P.; Ma, C.Y.; Guo, L.; Tan, J.F.; Peng, Q.H.; Lin, Z.
Cloning of a caffeoyl-coenzyme A O-methyltransferase from Camellia sinensis and analysis of its catalytic activity
J. Zhejiang Univ. Sci. B
16
103-112
2015
Camellia sinensis
Manually annotated by BRENDA team
Zhang, J.; Erickson, L.
Harvest-inducibility of the promoter of alfalfa S-adenosyl-L-methionine: Trans-caffeoyl-CoA3-O-methyltransferase gene
Mol. Biol. Rep.
39
2489-2495
2012
Medicago sativa
Manually annotated by BRENDA team
Brandt, W.; Manke, K.; Vogt, T.
A catalytic triad - Lys-Asn-Asp - is essential for the catalysis of the methyl transfer in plant cation-dependent O-methyltransferases
Phytochemistry
113
130-139
2015
Mesembryanthemum crystallinum (Q6YI95)
Manually annotated by BRENDA team
Ma, Q.H.; Luo, H.R.
Biochemical characterization of caffeoyl coenzyme A 3-O-methyltransferase from wheat
Planta
242
113-122
2015
Triticum aestivum
Manually annotated by BRENDA team
Wang, Z.; Ge, Q.; Chen, C.; Jin, X.; Cao, X.; Wang, Z.
Function analysis of caffeoyl-CoA O-methyltransferase for biosynthesis of lignin and phenolic acid in Salvia miltiorrhiza
Appl. Biochem. Biotechnol.
181
562-572
2017
Salvia miltiorrhiza (H9BEW0), Salvia miltiorrhiza
Manually annotated by BRENDA team
Yang, S.; Wu, T.; Ding, C.; Zhou, P.; Chen, Z.; Gou, J.
SAHH and SAMS form a methyl donor complex with CCoAOMT7 for methylation of phenolic compounds
Biochem. Biophys. Res. Commun.
520
122-127
2019
Arabidopsis thaliana (Q9C5D7), Arabidopsis thaliana Col-0 (Q9C5D7)
Manually annotated by BRENDA team
Xie, H.; Engle, N.L.; Venketachalam, S.; Yoo, C.G.; Barros, J.; Lecoultre, M.; Howard, N.; Li, G.; Sun, L.; Srivastava, A.C.; Pattathil, S.; Pu, Y.; Hahn, M.G.; Ragauskas, A.J.; Nelson, R.S.; Dixon, R.A.; Tschaplinski, T.J.; Blancaflor, E.B.; Tang, Y.
Combining loss of function of folylpolyglutamate synthetase1 and caffeoyl-CoA 3-O-methyltransferase1 for lignin reduction and improved saccharification efficiency in Arabidopsis thaliana
Biotechnol. Biofuels
12
108
2019
Arabidopsis thaliana
Manually annotated by BRENDA team
Xia, Y.; Liu, J.; Wang, Y.; Zhang, X.; Shen, Z.; Hu, Z.
Ectopic expression of Vicia sativa caffeoyl-CoA O-methyltransferase (VsCCoAOMT) increases the uptake and tolerance of cadmium in Arabidopsis
Environ. Exp. Bot.
145
47-53
2018
Vicia sativa
-
Manually annotated by BRENDA team
Rakoczy, M.; Femiak, I.; Alejska, M.; Figlerowicz, M.; Podkowinski, J.
Sorghum CCoAOMT and CCoAOMT-like gene evolution, structure, expression and the role of conserved amino acids in protein activity
Mol. Genet. Genomics
293
1077-1089
2018
Sorghum bicolor
Manually annotated by BRENDA team
Xu, R.X.; Zhao, Y.; Gao, S.; Zhang, Y.Y.; Li, D.D.; Lou, H.X.; Cheng, A.X.
Functional characterization of a plastidal cation-dependent O-methyltransferase from the liverwort Plagiochasma appendiculatum
Phytochemistry
118
33-41
2015
Plagiochasma appendiculatum (A0A0U2YR01), Plagiochasma appendiculatum
Manually annotated by BRENDA team
Liu, H.; Xu, R.X.; Zhang, X.S.; Zhu, T.T.; Lou, H.X.; Cheng, A.X.
The identification and functional characterization of three liverwort class I O-methyltransferases
Phytochemistry
159
190-198
2019
Marchantia paleacea, Haplomitrium mnioides, Marchantia emarginata, Plagiochasma appendiculatum (A0A0U2YR01), Plagiochasma appendiculatum
Manually annotated by BRENDA team
Shaipulah, N.F.; Muhlemann, J.K.; Woodworth, B.D.; Van Moerkercke, A.; Verdonk, J.C.; Ramirez, A.A.; Haring, M.A.; Dudareva, N.; Schuurink, R.C.
CCoAOMT down-regulation activates anthocyanin biosynthesis in Petunia
Plant Physiol.
170
717-731
2016
Petunia x hybrida
Manually annotated by BRENDA team
Wang, G.F.; Balint-Kurti, P.J.
Maize homologs of CCoAOMT and HCT, two key enzymes in lignin biosynthesis, form complexes with the NLR Rp1 protein to modulate the defense response
Plant Physiol.
171
2166-2177
2016
Zea mays (A0A172Q4R0), Zea mays
Manually annotated by BRENDA team
Walker, A.M.; Sattler, S.A.; Regner, M.; Jones, J.P.; Ralph, J.; Vermerris, W.; Sattler, S.E.; Kang, C.
The structure and catalytic mechanism of Sorghum bicolor caffeoyl-CoA O-methyltransferase
Plant Physiol.
172
78-92
2016
Sorghum bicolor (C5Z4W3), Sorghum bicolor
Manually annotated by BRENDA team
Giordano, D.; Provenzano, S.; Ferrandino, A.; Vitali, M.; Pagliarani, C.; Roman, F.; Cardinale, F.; Castellarin, S.D.; Schubert, A.
Characterization of a multifunctional caffeoyl-CoA O-methyltransferase activated in grape berries upon drought stress
Plant Physiol. Biochem.
101
23-32
2016
Vitis vinifera (Q43237), Vitis vinifera
Manually annotated by BRENDA team
Zhang, X.S.; Ni, R.; Wang, P.Y.; Zhu, T.T.; Sun, C.J.; Lou, H.X.; Cheng, A.X.
Isolation and functional characterization of two caffeoyl coenzyme A 3-O-methyltransferases from the fern species Polypodiodes amoena
Plant Physiol. Biochem.
136
169-177
2019
Goniophlebium amoenum (A0A4Y5R9F4), Goniophlebium amoenum
Manually annotated by BRENDA team
Ma, Q.; Luo, H.
Biochemical characterization of caffeoyl coenzyme A 3-O-methyltransferase from wheat
Planta
242
113-122
2015
Triticum aestivum
Manually annotated by BRENDA team