2.1.1.101: macrocin O-methyltransferase
This is an abbreviated version!
For detailed information about macrocin O-methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.101
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2.1.1.101
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tylosin
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fradiae
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macrolide
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cosmid
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pharmacology
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conversions
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agriculture
- 2.1.1.101
- tylosin
- fradiae
-
macrolide
-
cosmid
- pharmacology
-
conversions
- agriculture
Reaction
Synonyms
macrocin methyltransferase, S-adenosyl-L-methionine-macrocin O-methyltransferase
ECTree
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Systematic Name
Systematic Name on EC 2.1.1.101 - macrocin O-methyltransferase
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S-adenosyl-L-methionine:macrocin 3'''-O-methyltransferase
Requires Mg2+, Mn2+ or Co2+. The 3-hydroxy group of the 2-O-methyl-6-deoxy-D-allose moiety in the macrolide antibiotic macrosin acts as methyl acceptor, generating tylosin, another macrolide antibiotic. Isolated from the bacterium Streptomyces fradiae. Not identical with EC 2.1.1.102, demethylmacrocin O-methyltransferase.