2.1.1.10: homocysteine S-methyltransferase

This is an abbreviated version!
For detailed information about homocysteine S-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.10

2.1.1.10

methyltetrahydrofolate

mthfr

b12-dependent

cystathionine

n5-methyltetrahydrofolate

methylenetetrahydrofolate

tetrahydrofolate

mete

selenocysteine

methylmalonic

2.1.1.13

se-methylselenocysteine

medicine

Reaction

= 2 L-methionine

Synonyms

adenosylmethionine transmethylase, adenosylmethionine:homocysteine methyltransferase, AtHMT-1, AtHMT-2, AtHMT-3, BHMT, BHMT-2, F775_07039, HMT, HMT1, homocysteine methylase, homocysteine methyltransferase, homocysteine methyltransferase Mht1, homocysteine methyltransferase Sam4, homocysteine transmethylase, L-homocysteine S-methyltransferase, methylmethionine:homocysteine methyltransferase, S-adenosyl-L-methionine:L-homocysteine methyltransferase, S-adenosylmethionine homocysteine transmethylase, S-adenosylmethionine-homocysteine transmethylase, S-adenosylmethionine:homocysteine methyltransferase, S-methylmethionine homocysteine transmethylase, S-methylmethionine: homocysteine methyltransferase, S-methylmethionine: homocysteine S-methyltransferase, SMM:homocysteine S-methyltransferase, YagD, YagD protein

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.10 homocysteine S-methyltransferase

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Results	in table
8	Activating Compound
2746	AA Sequence
1	Application
1	CAS Registry Number
9	Cloned(Commentary)
1	Crystallization (Commentary)
4	Disease/ Diagnostics
1	Expression
3	General Information
1	General Stability
15	Inhibitors
15	KM Value [mM]
4	Localization
8	Metals/Ions
10	Molecular Weight [Da]
24	Natural Substrates/ Products (Substrates)
32	Organism
7	Pathway
4	PDB ID
6	pH Optimum
1	pH Range
1	pI Value
4	Protein Variants
3	Purification (Commentary)
2	Reaction
1	Reaction Type
31	Reference
17	Source Tissue
18	Specific Activity [micromol/min/mg]
69	Substrates and Products (Substrate)
7	Subunits
30	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
3	Turnover Number [1/s]

Localization

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Localization on EC 2.1.1.10 - homocysteine S-methyltransferase

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cytoplasm

Rattus norvegicus

O09171

mainly cytoplasmic localization in liver

in most tissues, low expression of BHMT coincides with a preferential nuclear localization of the protein

5634

756095