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1.8.4.2: protein-disulfide reductase (glutathione)

This is an abbreviated version!
For detailed information about protein-disulfide reductase (glutathione), go to the full flat file.

Word Map on EC 1.8.4.2

Reaction

2 glutathione +

protein-disulfide
=
glutathione-disulfide
+
protein-dithiol

Synonyms

BbdC, BdbD, C1orf31, CatA protein, ccdA associated thiol-disulfide oxidoreductase, COA6, DcbA, desulfothioredoxin, DIP1880, disulfide bond-forming thiol-disulfide oxidoreductase, disulphide interchange enzyme, DsbA, DsbA1, DsbA2, Dtrx, ERp57, GIT, glutathione-insulin transhydrogenase, glutathione-protein disulfide oxidoreductase, GRX1, GRX2, GRX3, GRX5, GRX6, GrxS12, GSH-dependent protein disulfide oxidoreductase, GSH-insulin transhydrogenase, HP_0231, insulin reductase, mcrophage migration inhibitory factor-2, MdbA, MdbACm, membrane-bound thiol-disulfide oxidoreductase, Mif-2, More, protein disulfide reductase (glutathione), protein disulfide transhydrogenase, protein-disulfide interchange enzyme, protein-disulfide isomerase/oxidoreductase, RCAP_rcc01743, reductase, protein disulfide (glutathione), ResA, SdbA, SGO_2006, SpyM18_2037, StoA, Streptococcus disulfide bond protein A, TDOR, thiol disulfide oxidoreductase, thiol-disulfide oxidoreductase, thiol-protein disulphide oxidoreductase, thiol:disulfide oxidoreductase, thiol:protein-disulfide oxidoreductase, WhiB1, WhiB1/Rv3219, YkuV, YMR244C-A

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.4 With a disulfide as acceptor
                1.8.4.2 protein-disulfide reductase (glutathione)

Cloned

Cloned on EC 1.8.4.2 - protein-disulfide reductase (glutathione)

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
characterization of cDNA for human glutathione-insulin transhydrogenase, amino acid sequence analysis, 94% homology to rat amino acid sequence
enzyme variants
-
expressed in Escherichia coli
-
expressed in Escherichia coli strain BL21(DE3)
-
expressed in Escherichia coli strain D5alpha
-
expressed in Escherichia coli TG1 and Rosetta-gami cells
-
expressed in Escherichia coli XL-1 Blue cells
-
expression from plasmid in bacterial expression system, amino acid analysis
-
expression from plasmid in Escherichia coli into the periplasm
-
expression in Escherichia coli
expression in Escherichia coli from plasmid
-
gene RCAP_rcc01743, recombiant overexpression in Escherichia coli
gene sdbA, recombinant expression of N-terminally His6-tagged wild-type and mutant enzymes in Escherichia coli strain XL-1 Blue
-
gene SGO_2006, DNA and amino acid sequence determination and analysis, quantitative real-time PCR, recombinant expression of N-terminally His6-tagged wild-type and mutant enzymes in Escherichia coli strain XL-1 Blue
overexpressed in Escherichia coli
-
overexpression from plasmid in Bacillus brevis, DNA sequence analysis
-
recombiant expression of codon optimized His-tagged wild-type and mutant enzymes in Escherichia coli strain BL21(DE3)
recombinant expression of GST-tagged wild-type and mutant enzymes in Escherichia coli strain BL21(DE3). Overexpression of the wild-type and mutant alleles of COA6 in control and COA6 patient fibroblasts
successfully expressed in Brevibacillus choshinensis extracellularly using the secretion vector pNCMO2, and in Escherichia coli intracellularly with an amino-terminal His-tag. Coexpression of CatA protein with recombinant hEGF in the Brevibacillus choshinensis production system increases the yield of native hEGF
-
systematic gene function analysis programm, expression of diverse constructs in Escherichia coli and Bacillus subtilis
-