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1.2
(S)-1-nonen-4-ol
-
MsrB, pH 8.0, 25°C, cofactor thioredoxin
0.14 - 2.2
acetyl-L-methionine (R)-sulfoxide N-methyl ester
-
0.00021
CDSP32
-
pH 8.0, 37°C, cosubstrate: dabsyl-L-methionine (R)-sulfoxide, MSRB1 activity
-
0.03 - 0.085
dabsyl-L-methionine (R)-S-oxide
0.02 - 0.06
dabsyl-L-methionine (R)-sulfoxide
0.0091 - 2
dithiothreitol
0.0028
glutaredoxin
30°C, pH 7.0, cosubstrate: N-acetyl-L-methionine-(R)-S-oxide
0.0068
glutaredoxin C4
-
isoform MSRB1 wild type enzyme
-
0.00053
glutaredoxin S12
-
pH 8.0, 37°C, cosubstrate: dabsyl-L-methionine (R)-sulfoxide, MSRB1 activity
-
1.451 - 67
L-methionine (R)-sulfoxide
56
L-methionine (R,S)-sulfoxide
-
MsrB activity of PILB, pH 8.0, 25°C
0.054 - 1.3
L-methionine-(R)-S-oxide
0.049
N-acetyl-L-methionine (R)-sulfoxide
0.043 - 0.429
N-acetyl-L-methionine-(R)-S-oxide
0.204
trypanothione disulfide
pH 7.5, 30°C, cosubstrate: N-acetyl-L-methionine-(R)-S-oxide, mutant enzyme C72S/C74S
1.8
tryparedoxin
-
pH 7.5, 30°C
-
0.0016 - 0.0021
tryparedoxin I
-
additional information
additional information
-
0.14
acetyl-L-methionine (R)-sulfoxide N-methyl ester
-
pH 5.5, 25°C
-
2.2
acetyl-L-methionine (R)-sulfoxide N-methyl ester
-
pH 8.0, 25°C
-
0.03
dabsyl-L-methionine (R)-S-oxide
mutant C11S, pH 7.5, 37°C
0.04
dabsyl-L-methionine (R)-S-oxide
mutant D164A, pH 7.5, 37°C
0.04
dabsyl-L-methionine (R)-S-oxide
mutant E165A, pH 7.5, 37°C
0.05
dabsyl-L-methionine (R)-S-oxide
wild-type, pH 7.5, 37°C
0.05
dabsyl-L-methionine (R)-S-oxide
mutant Y163A, pH 7.5, 37°C
0.06
dabsyl-L-methionine (R)-S-oxide
mutant Y163A//E165A, pH 7.5, 37°C
0.085
dabsyl-L-methionine (R)-S-oxide
isolated MrsB domain, pH 7.5, 37°C
0.02
dabsyl-L-methionine (R)-sulfoxide
pH 7.5, 37°C, mutant enzyme E339A
0.03
dabsyl-L-methionine (R)-sulfoxide
pH 7.5, 37°C, mutant enzyme Y343F
0.05
dabsyl-L-methionine (R)-sulfoxide
pH 7.5, 37°C, wild-type enzyme
0.05
dabsyl-L-methionine (R)-sulfoxide
pH 7.5, 37°C, mutant enzyme E193A/D197A
0.06
dabsyl-L-methionine (R)-sulfoxide
pH 7.5, 37°C, mutant enzyme D197A
0.06
dabsyl-L-methionine (R)-sulfoxide
pH 7.5, 37°C, mutant enzyme E193A
0.0091
dithiothreitol
-
recombinant enzyme, in 50 mM Tris-HCl, pH 8.0, at 37°C
0.03
dithiothreitol
wild type enzyme, in 50 mM sodium phosphate, pH 7.5, 50 mM NaCl, at 37°C
0.05
dithiothreitol
mutant enzyme C98S, in 50 mM sodium phosphate, pH 7.5, 50 mM NaCl, at 37°C
2
dithiothreitol
-
MsrB domain of MsrABTk, in the presence of 80 mM L-methionine (S)-sulfoxide
1.451
L-methionine (R)-sulfoxide
-
isoform MSRB4, pH and temperature not specified in the publication
2.093
L-methionine (R)-sulfoxide
-
isoform MSRB2, pH and temperature not specified in the publication
67
L-methionine (R)-sulfoxide
-
MsrB domain of MsrABTk, in the presence of 20 mM dithiothreiol
0.054
L-methionine-(R)-S-oxide
-
recombinant isozyme MsrB2, with dithioerythritol
0.079
L-methionine-(R)-S-oxide
-
recombinant isozyme MsrB1, with dithioerythritol
0.31
L-methionine-(R)-S-oxide
-
recombinant wild-type isozyme MsrB2 expressed in Escherichia coli
0.5
L-methionine-(R)-S-oxide
-
recombinant wild-type selenocysteine-containing isozyme MsrB1 expressed in NIH 3T3 cells
0.8
L-methionine-(R)-S-oxide
-
recombinant wild-type isozyme MsrB3 expressed in Escherichia coli
1
L-methionine-(R)-S-oxide
30°C, pH 7.0, cosubstrate: glutaredoxin
1
L-methionine-(R)-S-oxide
pH 7.5, 30°C, cosubstrate: tryparedoxin I
1.3
L-methionine-(R)-S-oxide
-
recombinant wild-type cysteine-containing isozyme MsrB1 expressed in NIH 3T3 cells
0.049
N-acetyl-L-methionine (R)-sulfoxide
-
isoform MSRB2, pH and temperature not specified in the publication
0.049
N-acetyl-L-methionine (R)-sulfoxide
-
isoform MSRB4, pH and temperature not specified in the publication
0.043
N-acetyl-L-methionine-(R)-S-oxide
pH 7.5, 30°C, cosubstrate: trypanothione, mutant enzyme C72S/C74S
0.045
N-acetyl-L-methionine-(R)-S-oxide
pH 7.5, 30°C, cosubstrate: tryparedoxin I, mutant enzyme C72S
0.047
N-acetyl-L-methionine-(R)-S-oxide
pH 7.5, 30°C, cosubstrate: tryparedoxin I, mutant enzyme C74S
0.2
N-acetyl-L-methionine-(R)-S-oxide
pH 7.5, 30°C, cosubstrate: tryparedoxin I
0.21
N-acetyl-L-methionine-(R)-S-oxide
30°C, pH 7.0, cosubstrate: glutaredoxin
0.429
N-acetyl-L-methionine-(R)-S-oxide
-
pH 7.5, 30°C
0.004
thioredoxin
-
pH 8.0, 37°C
0.0055
thioredoxin
pH 7.5, 30°C, cosubstrate: N-acetyl-L-methionine-(R)-S-oxide
0.026
thioredoxin
-
pH 5.5, 25°C
0.026
thioredoxin
30°C, pH 7.0, cosubstrate: N-acetyl-L-methionine-(R)-S-oxide
0.034
thioredoxin
-
MsrB activity of PILB, pH 8.0, 25°C
0.058
thioredoxin
-
MsrB, pH 8.0, 25°C, substrate acetyl-L-methionine (R)-sulfoxide N-methyl ester
0.66
thioredoxin
wild type enzyme, in 50 mM sodium phosphate, pH 7.5, 50 mM NaCl, at 37°C
7
thioredoxin
-
pH 8.0, 25°C
7
thioredoxin
mutant enzyme C98S, in 50 mM sodium phosphate, pH 7.5, 50 mM NaCl, at 37°C
0.0016
tryparedoxin I
pH 7.5, 30°C, cosubstrate: N-acetyl-L-methionine-(R)-S-oxide, mutant enzyme C72S
-
0.0019
tryparedoxin I
pH 7.5, 30°C, cosubstrate: N-acetyl-L-methionine-(R)-S-oxide, mutant enzyme C74S
-
0.0021
tryparedoxin I
pH 7.5, 30°C, cosubstrate: N-acetyl-L-methionine-(R)-S-oxide
-
additional information
additional information
-
kinetics
-
additional information
additional information
-
kinetic mechanism
-
additional information
additional information
-
kinetic mechanism
-
additional information
additional information
-
kinetic mechanism
-
additional information
additional information
-
stopped flow kinetics, steady-state kinetics
-
additional information
additional information
-
thermodynamics and kinetics of wild-type and mutant MsrB
-
additional information
additional information
-
thermodynamics and kinetics of wild-type and mutant MsrB
-
additional information
additional information
-
thioredoxin- and DTT-dependent kinetics of wild-type and mutant enzymes, overview
-
additional information
additional information
-
thioredoxin- and DTT-dependent kinetics of wild-type and mutant enzymes, overview
-
additional information
additional information
-
reductase step kinetic parameters of the wild-type and mutated MsrB
-