1.8.4.11: peptide-methionine (S)-S-oxide reductase
This is an abbreviated version!
For detailed information about peptide-methionine (S)-S-oxide reductase, go to the full flat file.
Reaction
Synonyms
EC 1.8.4.6, ecdysone-induced protein 28/29 kDa, FMsr, LIC_10545, LIC_12978, linmsra1, linmsra2, LMJF_07_1140, methionine S-oxide reductase (S-form oxidizing), methionine sulfoxide reductase, methionine sulfoxide reductase A, methionine sulfoxide reductases A, methionine sulfoxide-S-reductase, methionine sulphoxide reductase, methionine sulphoxide reductase A, methionine-S-sulfoxide reductase, MetSO-L12 reductase, More, mrsA, MSR, MSR10, MSR180, MsrA, MSRA-1, MsrA/B, MsrA/MsrB, MsrA1, MSRA2, MSRA4, msrAB, MsrABTk, MsrBA, Peptide Met(O) reductase, peptide methionine S-sulfoxide reductase, peptide methionine sulfoxide reductase, peptide methionine sulfoxide reductase A, peptide methionine sulfoxide reductase type A, peptide methionine sulphoxide reductase, peptide-methionine (S)-S-oxide reductase, peptide-methionine sulfoxide reductase, PilA, PilB, PilB protein, PMSR, PMSRA, protein-methionine-S-oxide-reductase, sulindac reductase, TbmsrA, TCDM_14270
ECTree
1.8.4.11 peptide-methionine (S)-S-oxide reductaseAdvanced search results
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results (KCat KM Value
KCat KM Value on EC 1.8.4.11 - peptide-methionine (S)-S-oxide reductase
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kcat/KM VALUE [1/mMs-1] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.044
dabsyl-L-methionine (S)-S-oxide
mutant Y163A//E165A, pH 7.5, 37°C
87
dabsyl-L-methionine (S)-S-oxide
isolated MrsA domain, pH 0.75, 37°C
0.68
dabsyl-L-methionine (S)-sulfoxide
pH 7.5, 37°C, mutant enzyme D197A
0.77
dabsyl-L-methionine (S)-sulfoxide
pH 7.5, 37°C, mutant enzyme E193A
0.78
dabsyl-L-methionine (S)-sulfoxide
pH 7.5, 37°C, mutant enzyme E193A/D197A
0.8
dabsyl-L-methionine (S)-sulfoxide
pH 7.5, 37°C, mutant enzyme Y343F
1
dabsyl-L-methionine (S)-sulfoxide
pH 7.5, 37°C, wild-type enzyme
1.47
dabsyl-L-methionine (S)-sulfoxide
pH 7.5, 37°C, mutant enzyme E339A
0.0086
L-methionine (S)-sulfoxide
-
recombinant enzyme. isoform MSR180, at 30°C and pH 7.5
4.6
L-methionine (S)-sulfoxide
-
recombinant enzyme. isoform MSRA, at 30°C and pH 7.5
7.2
L-methionine (S)-sulfoxide
-
recombinant enzyme. isoform MSR10, at 30°C and pH 7.5
0.04
L-methionine-(S)-S-oxide
30°C, pH 7.0, cosubstrate: thioredoxin, mutant enzyme C25S
0.25
L-methionine-(S)-S-oxide
30°C, pH 7.0, cosubstrate: thioredoxin, wild-type enzyme
0.548
L-methionine-(S)-S-oxide
pH 7.5, 30°C, cosubstrate: tryparedoxin I
0.71
L-methionine-(S)-S-oxide
30°C, pH 7.0, cosubstrate: thioredoxin, wild-type enzyme
0.02
N-acetyl-L-methionine-(S)-S-oxide
30°C, pH 7.0, cosubstrate: thioredoxin, mutant enzyme C25S
0.14
N-acetyl-L-methionine-(S)-S-oxide
30°C, pH 7.0, cosubstrate: thioredoxin, wild-type enzyme
0.15
N-acetyl-L-methionine-(S)-S-oxide
30°C, pH 7.0, cosubstrate: thioredoxin, wild-type enzyme
0.258
N-acetyl-L-methionine-(S)-S-oxide
pH 7.5, 30°C, cosubstrate: tryparedoxin I
1.197
thioredoxin
-
in 20 mM Tris-HCl, pH 8.0, 30 mM KCl, 10 mM MgCl2, at 37°C
4.167
thioredoxin
pH 7.5, 30°C, cosubstrate: L-methionine-(S)-S-oxide
4.3
thioredoxin
mutant C194S of isoform E4, in 50 mM Tris-HCl (pH 8.0), at 28°C
4.9
thioredoxin
mutant C180S of isoform MSRA2, in 50 mM Tris-HCl (pH 8.0), at 28°C
5.1
thioredoxin
wild type isoform MSRA2, in 50 mM Tris-HCl (pH 8.0), at 28°C
6.9
thioredoxin
mutant C188S of isoform E4, in 50 mM Tris-HCl (pH 8.0), at 28°C
40
thioredoxin
30°C, pH 7.0, cosubstrate: N-acetyl-L-methionine-(S)-S-oxide, wild-type enzyme
42
thioredoxin
30°C, pH 7.0, cosubstrate: L-methionine-(S)-S-oxide, wild-type enzyme
46.5
thioredoxin
wild type isoform E4, in 50 mM Tris-HCl (pH 8.0), at 28°C
49.5
thioredoxin
mutant C180S of isoform E4, in 50 mM Tris-HCl (pH 8.0), at 28°C
50
thioredoxin
30°C, pH 7.0, cosubstrate: L-methionine-(S)-S-oxide, wild-type enzyme
56
thioredoxin
30°C, pH 7.0, cosubstrate: N-acetyl-L-methionine-(S)-S-oxide, wild-type enzyme
27.45
tryparedoxin I
pH 7.5, 30°C, cosubstrate: N-acetyl-L-methionine-(S)-S-oxide
-
77
tryparedoxin I
-
recombinant enzyme. isoform MSR180, at 30°C and pH 7.5
-
180
tryparedoxin I
-
recombinant enzyme. isoform MSR10, at 30°C and pH 7.5
-
