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1.8.1.B1: thioredoxin glutathione reductase

This is an abbreviated version!
For detailed information about thioredoxin glutathione reductase, go to the full flat file.

Word Map on EC 1.8.1.B1

Reaction

glutathione disulfide
+
NADPH
+
H+
= 2 glutathione +
NADP+

Synonyms

cTGR, DmTrxR, EgTGR, mTGR, SmTGR, TGR, TGRsec, thioredoxin glutathione reductase, thioredoxin-glutathione reductase, thioredoxin/glutathione reductase

ECTree

     1 Oxidoreductases
         1.8 Acting on a sulfur group of donors
             1.8.1 With NAD+ or NADP+ as acceptor
                1.8.1.B1 thioredoxin glutathione reductase

KCat KM Value

KCat KM Value on EC 1.8.1.B1 - thioredoxin glutathione reductase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3.1
2-hydroxyethyl disulfide
-
at 25°C in 0.1 M potassium phosphate (pH 7.4)
0.31 - 1.45
5,5'-dithio-bis(2-nitrobenzoic acid)
8.7 - 2800
5,5'-dithiobis(2-nitrobenzoic acid)
0.38 - 7500
glutathione disulfide
28 - 390
glutathione-hydroxyethyl disulfide
9.3
GSH
-
at 25°C in 0.1 M potassium phosphate (pH 7.4)
22 - 108
GSSG
34 - 7900
NADPH
5.2 - 1480
thioredoxin disulfide