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1.7.5.1: nitrate reductase (quinone)

This is an abbreviated version!
For detailed information about nitrate reductase (quinone), go to the full flat file.

Word Map on EC 1.7.5.1

Reaction

nitrate
+
a quinol
=
nitrite
+
a quinone
+
H2O

Synonyms

EC 1.7.99.4, gene narH, membrane-bound nitrate reductase, membrane-bound quinol:nitrate oxidoreductase, MSMEG_5140, NaR, NaR1, NarG, NarGHI, narH, NarI, NarZ, nitrate reducatse A, nitrate reductase A, nitrate reductase Z, NRA nitrate reductase A, NRZ, NRZ nitrate reductase, Pden_4236, quinol-nitrate oxidoreductase, quinol/nitrate oxidoreductase, quinol:nitrate oxidoreductase, SCO6532, SCO6533, SCO6534, SCO6535

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.5 With a quinone or similar compound as acceptor
                1.7.5.1 nitrate reductase (quinone)

Inhibitors

Inhibitors on EC 1.7.5.1 - nitrate reductase (quinone)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-n-heptyl-4-hydroxyquinoline N-oxide
azide
-
5 mM, 95-98% inhibition
cyanide
-
1 mM, 95-98% inhibition
diethyl dicarbonate
-
the quinol-dependent, but not the viologen dye dependent, activity is inhibited irreversibly by exposure to diethyl pyrocarbonate
KCN
-
1 mM, complete inhibition
NaN3
-
10 mM, complete inhibition
Pentachlorophenol
-
mixed inhibition
Stigmatellin
additional information
-
p-chloromercuribenzoate (0.5 mM) or 2-heptyl-4-hydroxyquinolin N-oxide (1 mM) are almost without effect on the purified enzyme tested with reduced viologen as electron donor
-