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1.7.1.16: nitrobenzene nitroreductase

This is an abbreviated version!
For detailed information about nitrobenzene nitroreductase, go to the full flat file.

Word Map on EC 1.7.1.16

Reaction

N-phenylhydroxylamine
+ 2 NADP+ +
H2O
=
nitrobenzene
 + 2 NADPH + 2 H+

Synonyms

cnbA, NbzA, NfsB, NTR, Oxygen-insensitive NAD(P)H nitroreductase

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.16 nitrobenzene nitroreductase

Inhibitors

Inhibitors on EC 1.7.1.16 - nitrobenzene nitroreductase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1-Naphthylamine
1 mM, 31% residual activity
2-mercaptoethanol
Ag+
-
about 70% inhibition
Cd2+
1 mM, no residual activity
CuSO4
0.5 mM, 78% residual activity
cysteine
1 mM, 87% residual activity
dicumarol
0.01 mM, 40% residual activity
EDTA
-
56.7% residual activity at 10 mM
Fe2+
-
78.9% residual activity at 10 mM
Fe3+
-
40% residual activity at 10 mM
glutathione
1 mM, 41% residual activity
Hg2+
-
about 70% inhibition
menadione
1 mM, 61% residual activity
N-ethylmaleimide
1 mM, 77% residual activity
neocuproin
1 mM, 39% residual activity
Ni2+
-
46.7% residual activity at 10 mM
nitrite
1 mM, 77% residual activity
p-hydroxymercuribenzoate
1 mM, 46% residual activity
potassium cyanate
0.5 mM, 75% residual activity
salicyl hydroxamate
1 mM, 6% residual activity
SDS
-
16.7% residual activity at 10 mM
Sodium azide
Thiourea
-
35.7% residual activity at 10 mM
Triton X-100
Tween 20
1% w/v, 64% residual activity
Urea
-
42.8% residual activity at 10 mM
Zn2+
-
49.8% residual activity at 10 mM
ZnSO4
1 mM, no residual activity
additional information
-
not inhibitory: Fe2+
-