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1.6.3.5: renalase

This is an abbreviated version!
For detailed information about renalase, go to the full flat file.

Word Map on EC 1.6.3.5

Reaction

1,2-dihydro-beta-NAD(P)
+
H+
+
O2
=
beta-NAD(P)+
+
H2O2

Synonyms

alphaNAD(P)H oxidase/anomerase, REN, Ren-1, Ren-2, Ren1, renalase-1, renalase-2, RnlS

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.3 With oxygen as acceptor
                1.6.3.5 renalase

Expression

Expression on EC 1.6.3.5 - renalase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
gonadotropin-releasing hormone antagonist, cetrorelix, represses renalase expression in mice ovaries and testes
knockout of leptin, an effector and modulator of steroid hormones and reproduction, causes a dramatic increase of renalase expression in mice testes
renalase expression is significantly increased in cancers of the pancreas, bladder and breast and in melanoma
-
the secretion of renalase in both plasma and urine is increased in patients with chronic kidney disease
-