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1.6.1.1: NAD(P)+ transhydrogenase (Si-specific)

This is an abbreviated version!
For detailed information about NAD(P)+ transhydrogenase (Si-specific), go to the full flat file.

Word Map on EC 1.6.1.1

Reaction

NADPH
+
NAD+
=
NADP+
+
NADH

Synonyms

energy-independent soluble pyridine nucleotide transhydrogenase, H+-thase, NAD transhydrogenase, NAD(P) transhydrogenase, NAD(P)(+) transhydrogenase [B-specific], NADH transhydrogenase, NADH-NADP-transhydrogenase, NADPH-NAD oxidoreductase, NADPH-NAD transhydrogenase, NADPH:NAD+ transhydrogenase, nicotinamide adenine dinucleotide (phosphate) transhydrogenase, nicotinamide nucleotide transhydrogenase, NNT, non-energy-linked transhydrogenase, pyridine nucleotide transferase, pyridine nucleotide transhydrogenase, soluble pyridine nucleotide transhydrogenase, soluble transhydrogenase, STH, SthA, transhydrogenase, transhydrogenase, nicotinamide adenine dinucleotide (phosphate), UdhA

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.1 With NAD+ or NADP+ as acceptor
                1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)

Reference

Reference on EC 1.6.1.1 - NAD(P)+ transhydrogenase (Si-specific)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Voordouw, G.; van der Vies, S.M.; Themmen, A.P.N.
Why are two different types of pyridine nucleotide transhydrogenase found in living organisms?
Eur. J. Biochem.
131
527-533
1983
Azotobacter vinelandii, Pseudomonas aeruginosa, Pseudomonas fluorescens
Manually annotated by BRENDA team
Voordouw, G.; de Haard, H.; Timmermans, J.A.M.; Veeger, C.; Zabel, P.
Dissociation and assembly of pyridine nucleotide transhydrogenase from Azotobacter vinelandii
Eur. J. Biochem.
127
267-274
1982
Azotobacter vinelandii
Manually annotated by BRENDA team
Voordouw, G.; van der Vies, S.M.; Eweg, J.K.; Veeger, C.; van Breemen, J.F.L.; van Bruggen, E.F.J.
Pyridine nucleotide transhydrogenase from Azotobacter vinelandii. Improved purification, physical properties and subunit arrangement in purified polymers
Eur. J. Biochem.
111
347-355
1980
Azotobacter vinelandii
Manually annotated by BRENDA team
Voordouw, G.; van der Vies, S.; Scholten, J.W.; Veeger, C.
Pyridine nucleotide transhydrogenase from Azotobacter vinelandii. Differences in properties between the purified and the cell-free extract enzyme
Eur. J. Biochem.
107
337-344
1980
Azotobacter vinelandii
Manually annotated by BRENDA team
Voordouw, G.; Veeger, C.; van Breemen, J.F.L.; van Bruggen, E.F.J.
Structure of pyridine nucleotide transhydrogenase from Azotobacter vinelandii
Eur. J. Biochem.
98
447-454
1979
Azotobacter vinelandii
Manually annotated by BRENDA team
Höjeberg, B.; Rydström, J.
Ca2+-dependent allosteric regulation of nicotinamide nucleotide transhydrogenase from Pseudomonas aeruginosa
Eur. J. Biochem.
77
235-241
1977
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Collins, P.A.; Knowles, C.J.
Transhydrogenase activity in the marine bacterium Beneckea natriegens
Biochim. Biophys. Acta
480
77-82
1977
Vibrio natriegens
Manually annotated by BRENDA team
Widmer, F.; Kaplan, N.O.
Regulatory properties of the pyridine nucleotide transhydrogenase from Pseudomonas aeruginosa. Kinetic studies and fluorescence titration
Biochemistry
15
4693-4699
1976
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Wermuth, B.; Kaplan, N.O.
Pyridine nucleotide transhydrogenase from Pseudomonas aeruginosa: purification by affinity chromatography and physicochemical properties
Arch. Biochem. Biophys.
176
136-143
1976
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Hoek, J.B.; Rydström, J.; Höjeberg, B.
Comparative studies on nicotinamide nucleotide transhydrogenase from different sources
Biochim. Biophys. Acta
333
237-245
1974
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Rydström, J.; Hoek, J.B.; Höjeberg, B.
Ca 2+ -dependent allosteric regulation of nicotinamide nucleotide transhydrogenase from Pseudomonas aeruginosa
Biochem. Biophys. Res. Commun.
52
421-429
1973
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Middleditch, L.E.; Atchison, R.W.; Chung, A.E.
Pyridine nucleotide transhydrogenase from Azotobacter vinelandii. Some aspects of its structure
J. Biol. Chem.
247
6802-6809
1972
Azotobacter vinelandii
Manually annotated by BRENDA team
Van den Broek, H.W.J.; Santema, J.S.; Wassink, J.H.; Veeger, C.
Pyridine-nucleotide transhydrogenase. 1. Isolation, purification and characterisation of the transhydrogenase from Azotobacter vinelandii
Eur. J. Biochem.
24
31-45
1971
Azotobacter vinelandii
Manually annotated by BRENDA team
Van den Broek, H.W.J.; van Breemen, J.F.L.; van Bruggen, E.F.J.; Veeger, C.
Pyridine-nucleotide transhydrogenase. 2. Electron-microscopic studies on the transhydrogenase from Azotobacter vinelandii
Eur. J. Biochem.
24
46-54
1971
Azotobacter vinelandii
Manually annotated by BRENDA team
Van den Broek, H.W.J.; Veeger, C.
Pyridine-nucleotide transhydrogenase. 5. Kinetic studies on transhydrogenase from Azotobacter vinelandii
Eur. J. Biochem.
24
72-82
1971
Azotobacter vinelandii
Manually annotated by BRENDA team
Cohen, P.T.; Kaplan, N.O.
Kinetic characteristics of the pyridine nucleotide transhydrogenase from Pseudomonas aeruginosa
J. Biol. Chem.
245
4666-4672
1970
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Cohen, P.T.; Kaplan, N.O.
Purification and properties of the pyridine nucleotide transhydrogenase from Pseudomonas aeruginosa
J. Biol. Chem.
245
2825-2836
1970
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Chung, A.E.
Pyridine nucleotide transhydrogenase from Azotobacter vinelandii
J. Bacteriol.
102
438-447
1970
Azotobacter vinelandii
Manually annotated by BRENDA team
French, C.E.; Boonstra, B.; Bufton, K.A.; Bruce, N.C.
Cloning, sequence, and properties of the soluble pyridine nucleotide transhydrogenase of Pseudomonas fluorescens
J. Bacteriol.
179
2761-2765
1997
Pseudomonas fluorescens
Manually annotated by BRENDA team
Bykova, N.V.; Rasmusson, A.G.; Igamberdiev, A.U.; Gardestrom, P.; Moller, I.M.
Two separate transhydrogenase activities are present in plant mitochondria
Biochem. Biophys. Res. Commun.
265
106-111
1999
Pisum sativum, Solanum tuberosum
Manually annotated by BRENDA team
Rydström, J.; Hoek, J.B.; Ernster, L.
Nicotinamide nucleotide transhydrogenases
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
13
51-88
1976
Azotobacter vinelandii, Azotobacter agilis, Azotobacter chroococcum, Chromatium sp., Pseudomonas aeruginosa, Pseudomonas fluorescens
-
Manually annotated by BRENDA team
Ichinose, H.; Kamiya, N.; Goto, M.
Enzymatic redox cofactor regeneration in organic media: functionalization and application of glycerol dehydrogenase and soluble transhydrogenase in reverse micelles
Biotechnol. Prog.
21
1192-1197
2005
Escherichia coli
Manually annotated by BRENDA team
Sanchez, A.M.; Andrews, J.; Hussein, I.; Bennett, G.N.; San, K.Y.
Effect of overexpression of a soluble pyridine nucleotide transhydrogenase (UdhA) on the production of poly(3-hydroxybutyrate) in Escherichia coli
Biotechnol. Prog.
22
420-425
2006
Escherichia coli
Manually annotated by BRENDA team
Mouri, T.; Shimizu, T.; Kamiya, N.; Goto, M.; Ichinose, H.
Design of a cytochrome P450BM3 reaction system linked by two-step cofactor regeneration catalyzed by a soluble transhydrogenase and glycerol dehydrogenase
Biotechnol. Prog.
25
1372-1378
2009
Escherichia coli
Manually annotated by BRENDA team
Cao, Z.; Song, P.; Xu, Q.; Su, R.; Zhu, G.
Overexpression and biochemical characterization of soluble pyridine nucleotide transhydrogenase from Escherichia coli
FEMS Microbiol. Lett.
320
9-14
2011
Escherichia coli, Escherichia coli (P27306)
Manually annotated by BRENDA team
Jan, J.; Martinez, I.; Wang, Y.; Bennett, G.; San, K.
Metabolic engineering and transhydrogenase effects on NADPH availability in Escherichia coli
Biotechnol. Prog.
29
1124-1130
2013
Escherichia coli (P27306), Escherichia coli
Manually annotated by BRENDA team
Yamaguchi, R.; Kato, F.; Hasegawa, T.; Katsumata, N.; Fukami, M.; Matsui, T.; Nagasaki, K.; Ogata, T.
A novel homozygous mutation of the nicotinamide nucleotide transhydrogenase gene in a Japanese patient with familial glucocorticoid deficiency
Endocr. J.
60
855-859
2013
Homo sapiens
Manually annotated by BRENDA team
Haverkorn van Rijsewijk, B.R.; Kochanowski, K.; Heinemann, M.; Sauer, U.
Distinct transcriptional regulation of the two Escherichia coli transhydrogenases PntAB and UdhA
Microbiology
162
1672-1679
2016
Escherichia coli, Escherichia coli BW25113
Manually annotated by BRENDA team
Zhao, H.; Zhou, F.; Xing, Q.; Cao, Z.; Liu, J.; Zhu, G.
The soluble transhydrogenase UdhA affecting the glutamate-dependent acid resistance system of Escherichia coli under acetate stress
Biol. Open
7
bio031856
2018
Escherichia coli (P27306), Escherichia coli
Manually annotated by BRENDA team