1.5.99.B2: proline dehydrogenase (acceptor)
This is an abbreviated version!
For detailed information about proline dehydrogenase (acceptor), go to the full flat file.
Reaction
Synonyms
APE_1267.1, dye-linked L-proline dehydrogenase, L-proDH, L-proline dehydrogenase, L-proline: FAD oxidoreductase, L-proline:FAD oxidoreductase, LPDH, PDH, PDH1, PDH2, PF1246, PF1798, PH1364, PH1751, PIG6, POX, Pro dehydrogenase, PRODH, ProDH1, ProDH2, proline dehydrogenase, proline oxidase, prub, PutA, TK0117, TK0122, TPpdhB, TPpdhB2, TtProDH
ECTree
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Activating Compound
Activating Compound on EC 1.5.99.B2 - proline dehydrogenase (acceptor)
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L-proline
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in the presence of L-proline, high POX activity is sufficient to induce mitochondria-mediated apoptosis
additional information
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POX mRNA expression, and the extent of POX induction is correlated with radical oxygen species level and cell death suggesting that POX-induced radical oxygen species formation is critical for the apoptotic cell death induced by PPARgamma activation
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