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1.5.3.17: non-specific polyamine oxidase

This is an abbreviated version!
For detailed information about non-specific polyamine oxidase, go to the full flat file.

Word Map on EC 1.5.3.17

Reaction

N1-acetylspermidine
+
O2
+
H2O
=
putrescine
+
3-acetamidopropanal
+
H2O2

Synonyms

AtPAO2, AtPAO3, AtPAO4, AtPAO5, Bjpao1, Bjpao2, EC 1.5.3.11, Fms1, LC036642, OsPAO1, PAO, PAO1, PAO2, PAO3, PAO5, polyamine oxidase 1, SelPAO5, slr5093, T-Spm oxidase, thermospermine oxidase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.3 With oxygen as acceptor
                1.5.3.17 non-specific polyamine oxidase

Application

Application on EC 1.5.3.17 - non-specific polyamine oxidase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
analysis
-
the seedling polyamine oxidase is used for development of colorimetric assay methods to determine total polyamine, i.e. spermidine and spermine, and spermine concentrations in whole blood of humans, respectively, mechanism, overview
medicine
-
the inhibitor MDL 72145 might be a chemical lead compound for the design of new chemotherapeutic agents against nematode infections
synthesis
-
application of simple guide molecules, being either covalently attached to polyamines or used as a supplement to the substrate mixtures, for controlling the enzyme's regioselectivity and stereospecificity