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1.5.1.6: formyltetrahydrofolate dehydrogenase

This is an abbreviated version!
For detailed information about formyltetrahydrofolate dehydrogenase, go to the full flat file.

Word Map on EC 1.5.1.6

Reaction

10-formyltetrahydrofolate
+
NADP+
 +
H2O
=
tetrahydrofolate
 +
CO2
 +
NADPH
 +
H+

Synonyms

10-FDH, 10-formyl tetrahydrofolate:NADP oxidoreductase, 10-formyl-H2PtGlu:NADP oxidoreductase, 10-formyl-H4folate dehydrogenase, 10-formyltetrahydrofolate dehydrogenase, 10-fTHF dehydrogenase, 10-FTHFDH, ALDH1L1, ALDH1L2, dehydrogenase, formyltetrahydrofolate, FBP-CI, FBP-CI proteins, FDH, folate-binding proteins, cytosol I, More, mtFDH, N10-formyltetrahydrofolate dehydrogenase, proteins, folate-binding, cytosol I

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.6 formyltetrahydrofolate dehydrogenase

Storage Stability

Storage Stability on EC 1.5.1.6 - formyltetrahydrofolate dehydrogenase

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STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-15°C, presence of 0.01 mM 2-mercaptoethanol, several weeks, stable
-
-20°C, 20% glycerol, over 12 months, no loss of activity
-
-20°C, 20% glycerol, several months, stable
-
-20°C, dialyzed against 0.01 M potassium phosphate buffer, pH 7.3, 40% glycerol, 0.1 M KCl, several weeks, stable
-
-20°C, stable for several months
-70°C, 0.05 M phosphate buffer, pH 7.2, 50%-saturated (NH4)2SO4, 20% glycerol, 1 mM EDTA, 0.1 mM dithioerythritol, 0.01 mM phenylmethanesulfonyl fluoride, several months, stable
-
4°C, stable for 2 weeks