1.5.1.44: festuclavine dehydrogenase

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For detailed information about festuclavine dehydrogenase, go to the full flat file.

Reaction

Synonyms

EasA, EasG, ergot alkaloid biosynthetic protein G, festuclavine synthase, festuclavine synthase I, festuclavine synthase II, FgaFS, ifgF1, ifgF2, isofumigaclavine biosynthesis cluster A protein F1, isofumigaclavine biosynthesis cluster A protein F2

ECTree

     1 Oxidoreductases

         1.5 Acting on the CH-NH group of donors

             1.5.1 With NAD⁺ or NADP⁺ as acceptor

                1.5.1.44 festuclavine dehydrogenase

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Results	in table
3	Activating Compound
7	AA Sequence
4	Cloned(Commentary)
10	Cofactor
28	General Information
7	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
51	Organism
3	Pathway
3	pH Optimum
2	Protein Variants
4	Purification (Commentary)
1	Reaction
27	Reference
27	Substrates and Products (Substrate)
13	Subunits
62	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

Engineering

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Engineering on EC 1.5.1.44 - festuclavine dehydrogenase

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

F176Y

Aspergillus fumigatus

-

the mutant produces agroclavine from chanoclavine-I aldehyde

719646

Y178F

Aspergillus fumigatus

-

the activity of the mutant is not qualitatively different from wild type enzyme

719646