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1.5.1.38: FMN reductase (NADPH)

This is an abbreviated version!
For detailed information about FMN reductase (NADPH), go to the full flat file.

Reaction

FMNH2
+
NADP+
=
FMN
+
NADPH
+
H+

Synonyms

(NADPH)-dependent flavin mononucleotide reductase, (NADPH)-dependent FMN reductase, BC_1619, EC 1.5.1.29, EC 1.6.8.1, flavin reductase P, FMN reductase, FRP, More, NAD(P)H:FMN reductase, NADPH specific FMN reductase, NADPH-flavin oxidoreductase, NADPH-FMN oxidoreductase, NADPH:FMN oxidoreductase, NADPH:FMN reductase, SsuE, ssueE, ycbP, ydgI

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.38 FMN reductase (NADPH)

Substrates Products

Substrates Products on EC 1.5.1.38 - FMN reductase (NADPH)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-thioFMN + NADPH + H+
2-thioFMNH2 + NADP+
show the reaction diagram
-
the holoenzyme reconstituted with 2-thioFMN is catalytically active in using either FMN or 2-thioFMN as a substrate
-
-
?
FAD + NADPH + H+
FADH2 + NADP+
show the reaction diagram
FMN + NADH + H+
FMNH2 + NAD+
show the reaction diagram
when NADH is the pyrimidinic substrate, a distinct activity maximum is obtained at an FMN concentration of 0.5 mM, whereas concentrations higher than 2.5 mM led to more than 60% decrease in specific activity
-
-
?
FMN + NADPH + H+
FMNH2 + NADP+
show the reaction diagram
FMNH2 + NADP+
FMN + NADPH + H+
show the reaction diagram
riboflavin + NADPH + H+
reduced riboflavin + NADP+
show the reaction diagram
additional information
?
-