1.5.1.31: berberine reductase
This is an abbreviated version!
For detailed information about berberine reductase, go to the full flat file.
Word Map on EC 1.5.1.31
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1.5.1.31
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alkaloid
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berberis
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columbamine
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s-scoulerine
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palmatine
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somniferum
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morphine
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jatrorrhizine
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isoquinoline
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s-reticuline
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methylenedioxy
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dehydrogenate
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flavoprotein
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compartmentation
-
papaver
-
synthesis
- 1.5.1.31
-
alkaloid
- berberis
- columbamine
-
s-scoulerine
- palmatine
- somniferum
- morphine
- jatrorrhizine
- isoquinoline
-
s-reticuline
-
methylenedioxy
-
dehydrogenate
- flavoprotein
-
compartmentation
-
papaver
- synthesis
Reaction
Synonyms
(R)-canadine synthase, (S)-tetrahydroprotoberberine oxidase, STOX
ECTree
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Substrates Products
Substrates Products on EC 1.5.1.31 - berberine reductase
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REACTION DIAGRAM
7,8-dihydroberberine + NADPH
canadine + NADP+
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at 64% of the activity with palmatine and NADPH
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r
berberine + NADH
canadine + NAD+
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at 59% of the activity with palmatine. At 15% of the activity with berberine and NADPH
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r
columbamine + NADPH
? + NADP+
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at 39% of the activity with palmatine and NADPH
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r
coptisine + NADPH
? + NADP+
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at 47% of the activity with palmatine and NADPH
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r
dehydroscoulerine + NADPH
? + NADP+
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at 5% of the activity with palmatine and NADPH
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-
r
dihydrosinactine + NADPH
? + NADP+
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at 52% of the activity with palmatine and NADPH
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r
jatrorrhizine + NADPH
? + NADP+
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at 25% of the activity with palmatine and NADPH
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-
r
canadine + NADP+
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at 59% of the activity with palmatine and NADPH
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r
berberine + NADPH
canadine + NADP+
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(R)-tetrahydroberberines are formed from protoberberines by a highly stereoselective reduction system
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r