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1.5.1.31: berberine reductase

This is an abbreviated version!
For detailed information about berberine reductase, go to the full flat file.

Word Map on EC 1.5.1.31

Reaction

(R)-canadine
+ 2 NADP+ =
Berberine
+ 2 NADPH +
H+

Synonyms

(R)-canadine synthase, (S)-tetrahydroprotoberberine oxidase, STOX

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.31 berberine reductase

Natural Substrates Products

Natural Substrates Products on EC 1.5.1.31 - berberine reductase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(R)-canadine + 2 NADP+
berberine + 2 NADPH + H+
show the reaction diagram
-
-
-
-
?
berberine + NADPH
canadine + NADP+
show the reaction diagram
-
(R)-tetrahydroberberines are formed from protoberberines by a highly stereoselective reduction system
-
r