1.5.1.28: Opine dehydrogenase
This is an abbreviated version!
For detailed information about Opine dehydrogenase, go to the full flat file.
Word Map on EC 1.5.1.28
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1.5.1.28
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arthrobacter
-
pecten
-
staphylopine
-
metallophore
-
scallop
-
strombine
-
tauropine
-
maximus
-
nad+-linked
-
mytilus
-
prochiral
-
photographs
-
databank
-
nicotianamine
-
precession
-
octopine
-
mussel
-
galloprovincialis
- 1.5.1.28
-
arthrobacter
-
pecten
- staphylopine
-
metallophore
- scallop
- strombine
- tauropine
- maximus
-
nad+-linked
-
mytilus
-
prochiral
-
photographs
-
databank
- nicotianamine
-
precession
- octopine
- mussel
- galloprovincialis
Reaction
Synonyms
Dehydrogenase, opine, N-(1-D-Carboxyethyl)-L-norvaline dehydrogenase, N-[1-(R)-(Carboxy)ethyl]-(S)-norvaline: NAD+ oxidoreductase (L-norvaline forming), ODH, OpDH
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1.5.1.28 Opine dehydrogenaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 1.5.1.28 - Opine dehydrogenase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(R,S)-2,3-Diaminopropionic acid + pyruvate + NADH
?
-
9.67% of the activity with S: (S)-norvaline
-
-
?
(R,S)-3-Aminobutanoate + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(R,S)-3-aminobutanoate + NAD+
-
0.68% of the activity with (S)-norvaline
-
-
?
(S)-2-aminobutyric acid + pyruvate + NADH
N-[1-(R)-(carboxy)ethyl]-(S)-2-aminobutyric acid + NAD+
(S)-Phenylalaninol + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-phenylalaninol + NAD+
-
0.63% of the activity with (S)-norvaline
-
-
?
(S)-Phenylglycine + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-phenylglycine + NAD+
-
4.4% of the activity with (S)-norvaline
-
-
?
beta-Chloro-(S)-Ala + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-beta-chloroalanine + NAD+
Gly + pyruvate + NADH
N-(carboxymethyl)-D-alanine + NAD+
-
5.3% of the activity with L-Met
-
-
r
L-Asp + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Asp + NAD+
-
1.2% of the activity with L-Met
-
-
r
L-Cys + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Cys + NAD+
-
39% of the activity with L-Met
-
-
r
L-Ser + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Ser + NAD+
-
39% of the activity with L-Met
-
-
r
L-Thr + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Thr + NAD+
-
50% of the activity with L-Met
-
-
r
O-phospho-(S)-Ser + pyruvate + NADH + H+
N-[1-(R)-(carboxy)ethyl]-(S)-O-phospho-Ser + NAD+
-
-
-
-
r
p-Phospho-(S)-Tyr + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(R,S)-p-phospho-(S)-Tyr + NAD+
-
0.64% of the activity with (S)-norvaline
-
-
?
phospho-(S)-Ser + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-phospho-Ser + NAD+
-
15.8% of the activity with (S)-norvaline
-
-
?
(S)-2-aminobutyric acid + pyruvate + NADH
N-[1-(R)-(carboxy)ethyl]-(S)-2-aminobutyric acid + NAD+
-
83.7% of the activity with (S)-norvaline
-
-
?
(S)-2-aminobutyric acid + pyruvate + NADH
N-[1-(R)-(carboxy)ethyl]-(S)-2-aminobutyric acid + NAD+
-
83.7% of the activity with (S)-norvaline
-
-
?
(S)-Norleucine + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-norleucine + NAD+
-
72.5% of the activity with (S)-norvaline
-
-
?
(S)-Norleucine + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-norleucine + NAD+
-
72.5% of the activity with (S)-norvaline
-
-
?
(S)-Norvaline + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-norvaline + NAD+
-
-
-
-
?
(S)-Norvaline + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-norvaline + NAD+
-
-
-
-
?
beta-Chloro-(S)-Ala + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-beta-chloroalanine + NAD+
-
53.1% of the activity with (S)-norvaline
-
-
?
beta-Chloro-(S)-Ala + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-beta-chloroalanine + NAD+
-
53.1% of the activity with (S)-norvaline
-
-
?
L-Ala + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Ala + NAD+
-
16.0% of the activity with (S)-norvaline
-
-
?
L-Ala + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Ala + NAD+
-
67% of the activity with L-Met
-
-
r
L-Ile + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Ile + NAD+
-
22.3% of the activity with (S)-norvaline
-
-
?
L-Ile + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Ile + NAD+
-
94% of the activity with L-Met
-
-
r
L-Ile + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Ile + NAD+
-
94% of the activity with L-Met
-
-
r
L-Leu + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Leu + NAD+
-
21.2% of the activity with (S)-norvaline
-
-
?
L-Leu + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Leu + NAD+
-
89% of the activity with L-Met
-
-
r
L-Leu + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Leu + NAD+
-
89% of the activity with L-Met
-
-
r
L-Met + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Met + NAD+
-
23.9% of the activity with (S)-norvaline
-
-
?
L-Phe + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Phe + NAD+
-
21.7% of the activity with (S)-norvaline
-
-
?
L-Phe + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Phe + NAD+
-
91% of the activity with L-Met
-
?
L-Phe + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Phe + NAD+
-
91% of the activity with L-Met
-
?
L-Val + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Val + NAD+
-
21.9% of the activity with (S)-norvaline
-
-
?
L-Val + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Val + NAD+
-
92% of the activity with L-Met
-
-
r
L-Val + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-Val + NAD+
-
92% of the activity with L-Met
-
-
r
O-Acetyl-(S)-Ser + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-O-acetyl-Ser + NAD+
-
35.8% of the activity with (S)-norvaline
-
-
?
O-Acetyl-(S)-Ser + pyruvate + NADH
N-[1-(R)-(Carboxy)ethyl]-(S)-O-acetyl-Ser + NAD+
-
35.8% of the activity with (S)-norvaline
-
-
?
additional information
?
-
-
the physiological role of this enzyme may be the degradation of opines of plant origin to yield NADH rather than the synthesis of the opines. The products 2-keto acid and L-amino acid can support the growth of the microorganism
-
-
?
