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1.5.1.28: Opine dehydrogenase

This is an abbreviated version!
For detailed information about Opine dehydrogenase, go to the full flat file.

Word Map on EC 1.5.1.28

Reaction

(2S)-2-{[1-(R)-Carboxyethyl]amino}pentanoate
+
NAD+
+
H2O
=
L-2-aminopentanoic acid
+
pyruvate
+
NADH
+
H+

Synonyms

Dehydrogenase, opine, N-(1-D-Carboxyethyl)-L-norvaline dehydrogenase, N-[1-(R)-(Carboxy)ethyl]-(S)-norvaline: NAD+ oxidoreductase (L-norvaline forming), ODH, OpDH

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.28 Opine dehydrogenase

Natural Substrates Products

Natural Substrates Products on EC 1.5.1.28 - Opine dehydrogenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
amino acid + pyruvate + NADH + H+
opine + NAD+ + H2O
show the reaction diagram
additional information
?
-
-
the physiological role of this enzyme may be the degradation of opines of plant origin to yield NADH rather than the synthesis of the opines. The products 2-keto acid and L-amino acid can support the growth of the microorganism
-
-
?