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1.5.1.25: thiomorpholine-carboxylate dehydrogenase

This is an abbreviated version!
For detailed information about thiomorpholine-carboxylate dehydrogenase, go to the full flat file.

Word Map on EC 1.5.1.25

Reaction

Thiomorpholine 3-carboxylate
+
NAD(P)+
=
3,4-dehydro-thiomorpholine-3-carboxylate
+
NAD(P)H
+
H+

Synonyms

CRYM, CtBP, cytosolic thyroid hormone binding protein, DELTA1-piperideine-2-carboxylate reductase, ketimine reductase, ketimine-reducing enzyme, KR/CRYM/CTBP, More, mu-crystallin, P2C reductase, PLP-dependent amino acid gamma-substitution enzyme, PYCR2, Pyr2C reductase, reductase, ketimine, THBP, thyroid hormone binding protein, Thyroid hormone-binding protein

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.25 thiomorpholine-carboxylate dehydrogenase

Reference

Reference on EC 1.5.1.25 - thiomorpholine-carboxylate dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Nardini, M.; Ricci, G.; Caccuri, A.M.; Solinas, S.P.; Vesci, L.; Cavallini, D.
Purification and characterization of a ketimine-reducing enzyme
Eur. J. Biochem.
173
689-694
1988
Sus scrofa
Manually annotated by BRENDA team
Nardini, M.; Ricci, G.; Vesci, L.; Pecci, L.; Cavallini, D.
Bovine brain ketimine reductase
Biochim. Biophys. Acta
957
286-292
1988
Bos taurus
Manually annotated by BRENDA team
Hallen, A.; Jamie, J.F.; Cooper, A.J.
Lysine metabolism in mammalian brain an update on the importance of recent discoveries
Amino Acids
45
1249-1272
2013
Bos taurus, Homo sapiens, Macropus giganteus, Mus musculus, Rattus norvegicus, Sus scrofa
Manually annotated by BRENDA team
Hallen, A.; Cooper, A.J.; Smith, J.R.; Jamie, J.F.; Karuso, P.
Ketimine reductase/CRYM catalyzes reductive alkylamination of alpha-keto acids, confirming its function as an imine reductase
Amino Acids
47
2457-2461
2015
Homo sapiens (Q14894)
Manually annotated by BRENDA team
Hallen, A.; Cooper, A.J.; Jamie, J.F.; Karuso, P.
Insights into enzyme catalysis and thyroid hormone regulation of cerebral ketimine reductase/mu-crystallin under physiological conditions
Neurochem. Res.
40
1252-1266
2015
Bos taurus, Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Hallen, A.; Cooper, A.J.
Reciprocal control of thyroid binding and the pipecolate pathway in the brain
Neurochem. Res.
42
217-243
2017
Mus musculus (O54983), Homo sapiens (Q14894)
Manually annotated by BRENDA team