1.5.1.25: thiomorpholine-carboxylate dehydrogenase

This is an abbreviated version!
For detailed information about thiomorpholine-carboxylate dehydrogenase, go to the full flat file.

Word Map on EC 1.5.1.25

1.5.1.25

thyroid

nadph-dependent

bioavailability

cerebral

unsaturated

ovine

l-cystathionine

Reaction

3,4-dehydro-thiomorpholine-3-carboxylate

Synonyms

CRYM, CtBP, cytosolic thyroid hormone binding protein, DELTA1-piperideine-2-carboxylate reductase, ketimine reductase, ketimine-reducing enzyme, KR/CRYM/CTBP, More, mu-crystallin, P2C reductase, PLP-dependent amino acid gamma-substitution enzyme, PYCR2, Pyr2C reductase, reductase, ketimine, THBP, thyroid hormone binding protein, Thyroid hormone-binding protein

ECTree

1 Oxidoreductases

1.5 Acting on the CH-NH group of donors

1.5.1 With NAD⁺ or NADP⁺ as acceptor

1.5.1.25 thiomorpholine-carboxylate dehydrogenase

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Results	in table
1144	AA Sequence
1	CAS Registry Number
26	Cofactor
2	Crystallization (Commentary)
2	Expression
25	General Information
2	General Stability
1	IC50 Value
36	Inhibitors
4	kcat/KM [mM/s]
13	Ki Value [mM]
15	KM Value [mM]
14	Localization
4	Molecular Weight [Da]
30	Natural Substrates/ Products (Substrates)
14	Organism
6	PDB ID
11	pH Optimum
1	pH Range
6	Purification (Commentary)
9	Reaction
3	Reaction Type
14	Reference
27	Source Tissue
3	Specific Activity [micromol/min/mg]
2	Storage Stability
57	Substrates and Products (Substrate)
4	Subunits
73	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
4	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 1.5.1.25 - thiomorpholine-carboxylate dehydrogenase

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3,3',5'-L-triiodothyronine

2 entries

3,5,3'-L-triiodothyronine

2 entries

3,5,3'-triiodothyronine

9 entries

3,5-diiodo-L-tyrosine

2 entries

3,5-diiodothyronine

Homo sapiens

competitive inhibition

743354

3,5-L-diiodothyronine

Homo sapiens

Q14894

743355

4,5-dibromopyrrole-2-carboxylate

3 entries

DELTA1-piperideine 2-carboxylate

substrate inhibition

L-thyroxine

L-tyrosine

picolinate

pyrrole-2-carboxylate

3 entries

S-(2-aminoethyl)-L-cysteine ketimine

Homo sapiens

substrate inhibition

743354

Triton X-100

Sus scrofa

irreversible inactivation

440358

additional information

3 entries