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1.5.1.17: alanopine dehydrogenase

This is an abbreviated version!
For detailed information about alanopine dehydrogenase, go to the full flat file.

Word Map on EC 1.5.1.17

Reaction

2,2'-iminodipropanoate
+
NAD+
+
H2O
=
L-alanine
+
pyruvate
+
NADH
+
H+

Synonyms

ADH, ALADH, AlaDHAm, ALPDH, Dehydrogenase, alanopine, meso-N-(1-Carboxyethyl)-alanine dehydrogenase

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.17 alanopine dehydrogenase

Inhibitors

Inhibitors on EC 1.5.1.17 - alanopine dehydrogenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(NH4)2SO4
-
200 mM, 16% inhibition
2-oxoglutarate
3-phosphoglycerate
-
-
AMP
-
competitive with respect to NADH
D-lactate
D-strombine
-
-
dihydroxyacetone phosphate
-
-
fructose 1,6-bisphosphate
-
-
KCl
-
200 mM, 33% inhibition
L-Ala
L-alanine
uncompetitive substrate inhibition
L-lactate
meso-Alanopine
NaCl
-
200 mM, 38% inhibition
NH4Cl
-
200 mM, 23% inhibition
oxamate
pyruvate
succinate
additional information
-
the enzyme activity in adductor muscle decreases following the marine-brackish gradient
-