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1.4.9.2: aralkylamine dehydrogenase (azurin)

This is an abbreviated version!
For detailed information about aralkylamine dehydrogenase (azurin), go to the full flat file.

Word Map on EC 1.4.9.2

Reaction

ArCH2NH2
+
H2O
 + 2 azurin =
ArCHO
 +
NH3
 + 2 reduced azurin

Synonyms

AADH, AauA, AauB, AMDH, aromatic amine dehydrogenase, dehydrogenase, arylamine, EC 1.4.99.4, quinohemoprotein amine dehydrogenase, tyramine dehydrogenase

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.9 With a copper protein as acceptor
                1.4.9.2 aralkylamine dehydrogenase (azurin)

Inhibitors

Inhibitors on EC 1.4.9.2 - aralkylamine dehydrogenase (azurin)

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,4-Dinitrophenylhydrazine
-
4-nitrophenylhydrazine
-
8-hydroxyquinoline
-
33% inhibition at 1 mM
aminoguanidine
-
-
beta-phenylethylamine
dopamine
-
substrate inhibition at higher concentrations
EDTA
-
13% inhibition at 1 mM
histamine
-
weak substrate inhibition above 1 mM
hydrazine
hydroxylamine
iodoacetamide
-
28% inhibition at 1 mM
Iproniazid
-
-
monoiodoacetate
-
15% inhibition at 1 mM
NaN3
-
30% inhibition at 1 mM
o-phenanthroline
-
17% inhibition at 1 mM
phenylhydrazine
Semicarbazide
serotonin
-
substrate inhibition at higher concentrations
tryptamine
tyramine