1.4.3.23: 7-chloro-L-tryptophan oxidase

This is an abbreviated version!
For detailed information about 7-chloro-L-tryptophan oxidase, go to the full flat file.

Reaction

Synonyms

RebO

ECTree

     1 Oxidoreductases

         1.4 Acting on the CH-NH₂ group of donors

             1.4.3 With oxygen as acceptor

                1.4.3.23 7-chloro-L-tryptophan oxidase

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Results	in table
122	AA Sequence
3	Cloned(Commentary)
3	Cofactor
4	kcat/KM [mM/s]
4	KM Value [mM]
3	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
3	Organism
9	Pathway
24	PDB ID
3	Purification (Commentary)
1	Reaction
3	Reference
11	Substrates and Products (Substrate)
3	Subunits
4	Synonyms
1	Systematic Name
4	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 1.4.3.23 - 7-chloro-L-tryptophan oxidase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

1-methyl-L-tryptophan + O2

?

Lentzea aerocolonigenes

Q8KHS0

-

698569

-

-

?

5-fluoro-L-tryptophan + O2

?

Lentzea aerocolonigenes

Q8KHS0

-

698569

-

-

?

5-methyl-DL-tryptophan + O2

?

Lentzea aerocolonigenes

Q8KHS0

-

698569

-

-

?

7-chloro-L-tryptophan + O2

2-imino-3-(7-chloroindol-3-yl)propanoate + H2O2

4 entries

L-Trp + O2

?

Lentzea aerocolonigenes

Q8KHS0

-

698569

-

-

?

L-tryptophan + O2

2-imino-3-(indol-3-yl)propanoate + H2O2

Lentzea aerocolonigenes

-

-

741771

-

-

?

additional information

?

-

Lentzea aerocolonigenes

Q8KHS0

L-tryptophanamide and N-acetyl-tryptophan are not accepted as substrates by RebO

698569

-

-

?

7-chloro-L-tryptophan + O2

2-imino-3-(7-chloroindol-3-yl)propanoate + H2O2

Lentzea aerocolonigenes

-

-

741771

-

-

?

7-chloro-L-tryptophan + O2

2-imino-3-(7-chloroindol-3-yl)propanoate + H2O2

Lentzea aerocolonigenes

Q8KHS0

-

696205

-

-

?

7-chloro-L-tryptophan + O2

2-imino-3-(7-chloroindol-3-yl)propanoate + H2O2

Lentzea aerocolonigenes

Q8KHS0

rebeccamycin biosynthetic pathway

696205, 698569

-

-

?

7-chloro-L-tryptophan + O2

2-imino-3-(7-chloroindol-3-yl)propanoate + H2O2

Lentzea aerocolonigenes

Q8KHS0

RebO is specific for the L-Trp enantiomer. 7-chloro-L-Trp is the preferred substrate

698569

-

-

?