Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.4.3.21: primary-amine oxidase

This is an abbreviated version!
For detailed information about primary-amine oxidase, go to the full flat file.

Word Map on EC 1.4.3.21

Reaction

RCH2NH2
+
H2O
 +
O2
=
RCHO
 +
NH3
 +
H2O2

Synonyms

AGAO, AMAO2, AMAO3, amine oxidase 1, amine oxidase, copper containing, AO1, AO2, AOC2, AOC3, BAO, benzylamine oxidase, bovine plasma amine oxidase, bovine serum amine oxidase, BPAO, BSAO, CAO, Copper amine oxidase, copper amine oxidase 1, copper amine oxidase 8, copper-containing amine oxidase, copper-containing AO, copper-containing monoamine oxidase, copper-dependent amine oxidase, copper/quinone containing amine oxidase, Cu/TPQ amine oxidase, CuAO, CuAO1, CuAO2, CuAO3, CuAO8, EC 1.4.3.6, ECAO, ELAO, GPAO, grass pea amine oxidase, Hansenula polymorpha amine oxidase, HPAO, hPAO-1, HPAO-2, lentil seedling amine oxidase, LSAO, MAO-N, More, OVAO, PAO, pea seedling amine oxidase, plasma amine oxidase, PrAO, primary amine oxidase, primary-amine:oxygen oxidoreductase, PSAO, quinone- and copper-containing amine oxidase, quinone-containing copper amine oxidase, quinone-dependent amine oxidase, quinoprotein copper-containing amine oxidase, RAO, sainfoin amine oxidase, semicarbazide-sensitive amine oxidase, semicarbazide-sensitive amine oxidase/vascular adhesion protein-1, SSAO, SSAO/VAP-1, TPQ-containing CuAO, tynA, tyramine oxidase, copper-requiring, VAP-1, vascular adhesion protein 1, vascular adhesion protein-1

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.21 primary-amine oxidase

IC50 Value

IC50 Value on EC 1.4.3.21 - primary-amine oxidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.000055
(2-methylprop-2-en-1-yl)hydrazine
Bos taurus
-
-
0.000002 - 0.000035
(2-phenylprop-2-en-1-yl)hydrazine
0.002
(2E)-3-chloroprop-2-en-1-amine
Bos taurus
-
-
0.00029
(2E)-3-fluoro-4-phenoxybut-2-en-1-amine
Homo sapiens
-
pH and temperature not specified in the publication
0.082
(2E)-4-phenoxybut-2-en-1-amine
Homo sapiens
-
pH and temperature not specified in the publication
0.011
(2Z)-3-chloroprop-2-en-1-amine
Bos taurus
-
-
0.02
(2Z)-3-fluoro-4-phenoxybut-2-en-1-amine
Homo sapiens
-
pH and temperature not specified in the publication
0.1
(2Z)-4-phenoxybut-2-en-1-amine
Homo sapiens
-
IC 50 above 0.1 mM, pH and temperature not specified in the publication
0.00014
(4-[[(2E)-4-amino-2-fluorobut-2-en-1-yl]oxy]phenyl)(pyrrolidin-1-yl)methanone
Homo sapiens
-
pH and temperature not specified in the publication
0.000004 - 0.000043
(Z)-3-fluoro-2-(4-methoxybenzyl)allylamine hydrochloride
0.00086
1-(2,5-dihydro-1H-pyrrol-3-yl)isoquinoline
Bos taurus
-
-
0.00017 - 0.33
1-(3,5-diethoxypyridin-4-yl)methanamine dihydrochloride
0.000078
1-(isoquinolin-1-ylcarbonyl)pyrrolidine-2-carboxamide
Homo sapiens
-
-
0.00023
1-ethyl-2-[2-(4-fluorophenyl)prop-2-en-1-yl]hydrazine
Rattus norvegicus
-
-
0.0000017
1-[2-(4-fluorophenyl)prop-2-en-1-yl]-2-methylhydrazine
Rattus norvegicus
-
-
0.00013
1-[3,5-bis(ethylsulfanyl)pyridin-4-yl]methanamine dihydrochloride
Sus scrofa
-
-
0.0016
1-[3,5-bis(tert-butylsulfanyl)pyridin-4-yl]methanamine dihydrochloride
Sus scrofa
-
-
0.005
1-[3-(benzyloxy)-5-ethoxypyridin-4-yl]methanamine dihydrochloride
Sus scrofa
-
-
0.00075
2-(2,5-dihydro-1H-pyrrol-3-yl)pyridine
Bos taurus
-
-
0.0000026
2-(4-[2-[2-(acetylamino)-2,3-dihydro-1,3-thiazol-4-yl]ethyl]phenyl)-N-[amino(imino)methyl]acetamide
Homo sapiens
-
-
0.00009
2-(aminooxy)-1-(3,4-dimethoxyphenyl)ethanol
Bos taurus
-
-
0.00005
2-(aminooxy)-1-phenylethanol
Bos taurus
-
-
5
2-(methylamino)ethanethiol
Bos taurus
-
in 100 mM potassium phosphate buffer, pH 7.2, at 30°C
1.3
2-(methylthio)ethylamine
Bos taurus
-
in 100 mM potassium phosphate buffer, pH 7.2, at 30°C
0.000004
2-([[4-(1,1-dimethylpropyl)phenyl]sulfonyl]amino)-N,3-dihydroxybutanamide
Homo sapiens
-
-
0.000015
2-amino-N-[2-fluoro-3-(trifluoromethyl)benzyl]acetamide
Rattus norvegicus
-
-
0.00001
2-amino-N-[2-fluoro-5-(trifluoromethyl)benzyl]acetamide
Rattus norvegicus
-
-
0.000033
2-amino-N-[3-fluoro-5-(trifluoromethyl)benzyl]acetamide
Rattus norvegicus
-
-
0.00018
2-amino-N-[4-fluoro-3-(trifluoromethyl)benzyl]acetamide
Rattus norvegicus
-
-
1.5
2-ethylaminobenzylamine dihydrochloride
Ogataea angusta
-
0.75
2-methylaminobenzylamine dihydrochloride
Ogataea angusta
-
0.000125
2-[(biphenyl-4-ylacetyl)amino]pentanedioic acid
Homo sapiens
-
-
0.0032
3,3'-[[4-(aminomethyl)pyridine-3,5-diyl]bis(oxy)]dipropan-1-ol dihydrochloride
Sus scrofa
-
-
0.1
3-(1-piperidinyl)-4-aminomethylpyridine dihydrochloride hemihydrate
Sus scrofa
-
-
0.0015
3-(2,5-dihydro-1H-pyrrol-3-yl)pyridine
Bos taurus
-
-
0.042
3-(4-methoxyphenyl)-N-methyl-5-(1H-pyrrol-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Rattus norvegicus
-
-
0.016
3-amino-4-aminomethylpyridine dihydrochloride
Sus scrofa
-
-
0.3
3-aminopropanethiol
Bos taurus
-
in 100 mM potassium phosphate buffer, pH 7.2, at 30°C
0.01
3-bromoprop-2-yn-1-amine
Bos taurus
-
-
0.079 - 1
3-cycloheptylamino-4-aminomethylpyridine dihydrochloride monohydrate
0.0056
3-cyclohexylamino-4-aminomethylpyridine dihydrochloride monohydrate
Sus scrofa
-
-
0.0056 - 0.89
3-cyclohexylmethylamino-4-aminomethylpyridine dihydrochloride monohydrate
0.016 - 0.7
3-cyclopentylamino-4-aminomethylpyridine dihydrochloride hemihydrate
0.002 - 0.087
3-ethylamino-4-aminomethylpyridine dihydrochloride
0.00071 - 0.053
3-methylamino-4-aminomethylpyridine dihydrochloride
0.1
3-[(1-methylethyl)amino]-4-aminomethylpyridine dihydrochloride
Sus scrofa
-
-
0.0005
3-[2-(3-methoxyphenyl)ethyl]-2,5-dihydro-1H-pyrrole
Rattus norvegicus
-
-
0.00015
4,4'-[[4-(aminomethyl)pyridine-3,5-diyl]bis(oxy)]dibutan-1-ol dihydrochloride
Sus scrofa
-
-
0.025
4-(2-naphthyloxy)but-2-yn-1-amine
Bos taurus
-
-
0.02
4-(4-methoxyphenoxy)but-2-yn-1-amine
Bos taurus
-
-
0.022
4-(4-methylphenoxy)but-2-yn-1-amine
Bos taurus
-
-
0.02
4-(4-nitrophenoxy)but-2-yn-1-amine
Bos taurus
-
-
0.35
4-(aminomethyl)-N,N'-dibutylpyridine-3,5-diamine dihydrochloride
Sus scrofa
-
-
0.03
4-(aminomethyl)-N,N'-diethylpyridazine-3,5-diamine
Homo sapiens
-
pH not specified in the publication, temperature not specified in the publication
0.00002 - 0.35
4-(aminomethyl)-N,N'-diethylpyridine-3,5-diamine dihydrochloride
0.00044 - 0.1
4-(aminomethyl)-N,N'-dimethylpyridine-3,5-diamine dihydrochloride
0.0017
4-(aminomethyl)-N-methylpyridine-3,5-diamine dihydrochloride
Sus scrofa
-
-
0.000146
4-amino-3-hydroxy-N-(3-phenylpropyl)benzamide
Homo sapiens
-
-
0.013
4-aminobut-2-ynenitrile
Bos taurus
-
-
0.0001
4-bromo-N-[2-(hydroxyamino)-2-oxoethyl]benzamide
Homo sapiens
-
-
0.2
4-phenoxybut-2-yn-1-amine
Bos taurus
-
-
0.00037
4-[[(2E)-4-amino-2-fluorobut-2-en-1-yl]oxy]-N,N-dimethylbenzamide
Homo sapiens
-
pH and temperature not specified in the publication
0.00004
4-[[(2E)-4-amino-2-fluorobut-2-en-1-yl]oxy]-N-(1-phenylethyl)benzamide
Homo sapiens
-
pH and temperature not specified in the publication
0.00026
4-[[(2E)-4-amino-2-fluorobut-2-en-1-yl]oxy]-N-benzyl-N-methylbenzamide
Homo sapiens
-
pH and temperature not specified in the publication
0.00008
4-[[(2E)-4-amino-2-fluorobut-2-en-1-yl]oxy]-N-benzylbenzamide
Homo sapiens
-
pH and temperature not specified in the publication
0.00001
4-[[(2E)-4-amino-2-fluorobut-2-en-1-yl]oxy]-N-cyclohexylbenzamide
Homo sapiens
-
pH and temperature not specified in the publication
0.00002
4-[[(2E)-4-amino-2-fluorobut-2-en-1-yl]oxy]-N-cyclopentylbenzamide
Homo sapiens
-
pH and temperature not specified in the publication
0.00107
4-[[(2E)-4-amino-2-fluorobut-2-en-1-yl]oxy]benzamide
Homo sapiens
-
pH and temperature not specified in the publication
0.000575
5-amino-2-hydroxy-N-(3-phenylpropyl)benzamide
Homo sapiens
-
-
1
amikacin
Escherichia coli
-
at pH 7.4 and 30°C
0.00024
BTT-2052
Escherichia coli
-
at pH 7.4 and 30°C
0.0029
but-3-yn-1-amine
Bos taurus
-
-
0.00125
buta-2,3-dien-1-amine
Bos taurus
-
-
0.0125
cysteamine
Bos taurus
-
in 100 mM potassium phosphate buffer, pH 7.2, at 30°C
0.00658
geraniin
Bos taurus
-
pH 7.4, 37°C
3.8
kanamycin
Escherichia coli
-
at pH 7.4 and 30°C
0.00002
mofegiline
Homo sapiens
-
pH and temperature not specified in the publication
0.000054
N,3-dihydroxy-2-[(2-naphthylsulfonyl)amino]butanamide
Homo sapiens
-
-
0.225
N-allyl-3-(4-methoxyphenyl)-5-(1H-pyrrol-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Rattus norvegicus
-
-
0.17
N-ethyl-3-(4-methoxyphenyl)-5-(1H-pyrrol-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide
Rattus norvegicus
-
-
0.000033
N-[2-(hydroxyamino)-2-oxoethyl]-2-(2-methyl-1H-indol-3-yl)acetamide
Homo sapiens
-
-
0.0000053
N-[4-(2-[4-[(2-amino-1H-imidazol-5-yl)methyl]phenyl]ethyl)-1,3-thiazol-2-yl]acetamide
Homo sapiens
-
-
0.0000045
N-[4-[2-(4-carbamimidamidophenyl)ethyl]-5-(4-sulfamoylbenzyl)-1,3-thiazol-2-yl]acetamide
Homo sapiens
-
-
0.00015
N-[4-[2-(4-[[amino(imino)methyl]amino]phenyl)ethyl]-1,3-thiazol-2-yl]acetamide
Homo sapiens
-
-
0.0007
Semicarbazide
Escherichia coli
-
at pH 7.4 and 30°C
0.8
tobramycin
Escherichia coli
-
at pH 7.4 and 30°C
0.000005
[(2E)-3-fluoro-2-phenylprop-2-en-1-yl]hydrazine
Rattus norvegicus
-
-
0.000004
[2-(2-methylphenyl)prop-2-en-1-yl]hydrazine
Rattus norvegicus
-
-
0.000003
[2-(4-chlorophenyl)prop-2-en-1-yl]hydrazine
Rattus norvegicus
-
-
0.000006
[2-(4-fluorophenyl)prop-2-en-1-yl]hydrazine
Rattus norvegicus
-
-
additional information
additional information
-